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Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle
Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
* Author to whom correspondence should be addressed.
Received: 2 April 2013; in revised form: 21 May 2013 / Accepted: 21 May 2013 / Published: 30 May 2013
Abstract: The Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4. We describe the multiple roles of Brd4 in the papillomavirus lifecycle.
Keywords: Brd4; BET protein; HPV; papillomavirus; transcription; chromatin; replication; tethering; partitioning; bromodomain
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Cite This Article
MDPI and ACS Style
McBride, A.A.; Jang, M.K. Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle. Viruses 2013, 5, 1374-1394.
McBride AA, Jang MK. Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle. Viruses. 2013; 5(6):1374-1394.
McBride, Alison A.; Jang, Moon K. 2013. "Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle." Viruses 5, no. 6: 1374-1394.