Viruses 2013, 5(6), 1374-1394; doi:10.3390/v5061374
Review

Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle

Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
* Author to whom correspondence should be addressed.
Received: 2 April 2013; in revised form: 21 May 2013 / Accepted: 21 May 2013 / Published: 30 May 2013
(This article belongs to the Special Issue Chromatin Control of Viral Infection)
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Abstract: The Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4. We describe the multiple roles of Brd4 in the papillomavirus lifecycle.
Keywords: Brd4; BET protein; HPV; papillomavirus; transcription; chromatin; replication; tethering; partitioning; bromodomain

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MDPI and ACS Style

McBride, A.A.; Jang, M.K. Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle. Viruses 2013, 5, 1374-1394.

AMA Style

McBride AA, Jang MK. Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle. Viruses. 2013; 5(6):1374-1394.

Chicago/Turabian Style

McBride, Alison A.; Jang, Moon K. 2013. "Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle." Viruses 5, no. 6: 1374-1394.

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