Viruses 2013, 5(10), 2469-2482; doi:10.3390/v5102469
Article

West Nile Virus Antibody Prevalence in Horses of Ukraine

1 Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Südufer 10, D-17493 Greifswald-Insel Riems, Germany 2 Institute of Veterinary Medicine, National Academy of Agrarian Sciences of Ukraine, Donetska Str. 30, Kyiv, 03151 Ukraine 3 Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Epidemiology, Seestraße 55, D-16868 Wusterhausen, Germany 4 Institut für Virologie, Zentrum für Infektionsmedizin, Freie Universität Berlin, Philippstr. 13, D-14163 Berlin, Germany
* Author to whom correspondence should be addressed.
Received: 23 August 2013; in revised form: 30 September 2013 / Accepted: 1 October 2013 / Published: 4 October 2013
(This article belongs to the Section Animal Viruses)
PDF Full-text Download PDF Full-Text [357 KB, Updated Version, uploaded 4 October 2013 17:32 CEST]
The original version is still available [357 KB, uploaded 7 October 2013 18:18 CEST]
Abstract: West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years ago, yet the current epidemiological status is quite unclear. In this study, serum samples from over 300 equines were collected and screened in order to detect current WNV activity in Ukraine with the goal to estimate the risk of infection for humans and horses. Sera were tested by enzyme-linked immunosorbent assay (ELISA) and virus neutralization assay (NT) to detect WNV-specific antibodies. The results clearly revealed that WNV circulates in most of the regions from which samples were obtained, shown by a WNV seroprevalence rate of 13.5% of examined horses. This is the first topical report indicating the presence of WNV infections in horses in Ukraine, and the results of this study provide evidence of a widespread WNV circulation in this country.
Keywords: West Nile virus; neutralization; ELISA; serology; horse; Ukraine, prevalence, flavivirus

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Ziegler, U.; Skrypnyk, A.; Keller, M.; Staubach, C.; Bezymennyi, M.; Damiani, A.M.; Osterrieder, N.; Groschup, M.H. West Nile Virus Antibody Prevalence in Horses of Ukraine. Viruses 2013, 5, 2469-2482.

AMA Style

Ziegler U, Skrypnyk A, Keller M, Staubach C, Bezymennyi M, Damiani AM, Osterrieder N, Groschup MH. West Nile Virus Antibody Prevalence in Horses of Ukraine. Viruses. 2013; 5(10):2469-2482.

Chicago/Turabian Style

Ziegler, Ute; Skrypnyk, Artem; Keller, Markus; Staubach, Christoph; Bezymennyi, Maksym; Damiani, Armando M.; Osterrieder, Nikolaus; Groschup, Martin H. 2013. "West Nile Virus Antibody Prevalence in Horses of Ukraine." Viruses 5, no. 10: 2469-2482.

Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert