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Forty-Five Years of Marburg Virus Research
Department of Microbiology, School of Medicine and National Emerging Infectious Diseases Laboratories Institute, Boston University, 72 East Concord Street, Boston, MA 02118, USA
The authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 23 August 2012; in revised form: 19 September 2012 / Accepted: 25 September 2012 / Published: 1 October 2012
Abstract: In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg virus, is one of the most deadly human pathogens. This article provides a comprehensive overview of our current knowledge about Marburg virus disease ranging from ecology to pathogenesis and molecular biology.
Keywords: Marburg virus; filoviruses; epidemiology; ecology; clinical manifestations; virus structure; replication cycle; pathogenesis; animal models; vaccine development
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Brauburger, K.; Hume, A.J.; Mühlberger, E.; Olejnik, J. Forty-Five Years of Marburg Virus Research. Viruses 2012, 4, 1878-1927.
Brauburger K, Hume AJ, Mühlberger E, Olejnik J. Forty-Five Years of Marburg Virus Research. Viruses. 2012; 4(10):1878-1927.
Brauburger, Kristina; Hume, Adam J.; Mühlberger, Elke; Olejnik, Judith. 2012. "Forty-Five Years of Marburg Virus Research." Viruses 4, no. 10: 1878-1927.