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Viruses 2012, 4(10), 1878-1927; doi:10.3390/v4101878
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Forty-Five Years of Marburg Virus Research

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Received: 23 August 2012 / Revised: 19 September 2012 / Accepted: 25 September 2012 / Published: 1 October 2012
(This article belongs to the Special Issue Advances in Filovirus Research 2012)
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Abstract

In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg virus, is one of the most deadly human pathogens. This article provides a comprehensive overview of our current knowledge about Marburg virus disease ranging from ecology to pathogenesis and molecular biology.
Keywords: Marburg virus; filoviruses; epidemiology; ecology; clinical manifestations; virus structure; replication cycle; pathogenesis; animal models; vaccine development Marburg virus; filoviruses; epidemiology; ecology; clinical manifestations; virus structure; replication cycle; pathogenesis; animal models; vaccine development
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Brauburger, K.; Hume, A.J.; Mühlberger, E.; Olejnik, J. Forty-Five Years of Marburg Virus Research. Viruses 2012, 4, 1878-1927.

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