Next Article in Journal
Last Stop Before Exit – Hepatitis C Assembly and Release as Antiviral Drug Targets
Next Article in Special Issue
Neuraminidase Inhibitor Susceptibility Testing in Human Influenza Viruses: A Laboratory Surveillance Perspective
Previous Article in Journal
Hepatitis C Virus NS3/4A Protease Inhibitors: A Light at the End of the Tunnel
Previous Article in Special Issue
Animal Models for Influenza Virus Pathogenesis and Transmission
Viruses 2010, 2(8), 1766-1781; doi:10.3390/v2081766
Review

Antiviral Strategies for Pandemic and Seasonal Influenza

,
 and
*
Received: 11 June 2010 / Revised: 6 August 2010 / Accepted: 11 August 2010 / Published: 20 August 2010
(This article belongs to the Special Issue Antivirals Against Influenza)
Download PDF [259 KB, uploaded 12 May 2015]

Abstract

While vaccines are the primary public health response to seasonal and pandemic flu, short of a universal vaccine there are inherent limitations to this approach. Antiviral drugs provide valuable alternative options for treatment and prophylaxis of influenza. Here, we will review drugs and drug candidates against influenza with an emphasis on the recent progress of a host-targeting entry-blocker drug candidate, DAS181, a sialidase fusion protein.
Keywords: influenza virus; neuraminidase inhibitors; sialic acid; RNA polymerase influenza virus; neuraminidase inhibitors; sialic acid; RNA polymerase
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Hedlund, M.; Larson, J.L.; Fang, F. Antiviral Strategies for Pandemic and Seasonal Influenza. Viruses 2010, 2, 1766-1781.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert