Next Article in Journal
A Novel System for Identification of Inhibitors of Rift Valley Fever Virus Replication
Previous Article in Journal
Recent Advances in Hepatitis C Virus Cell Entry
Viruses 2010, 2(3), 710-730; doi:10.3390/v2030710

Complete Genomic Sequence of Bacteriophage Felix O1

, 2
, 3, 4
, 5
, 6
, 7
, 8
, 9
, 8,10
 and 11,*
Received: 12 December 2009 / Revised: 25 February 2010 / Accepted: 8 March 2010 / Published: 9 March 2010
Download PDF [502 KB, uploaded 9 March 2010]
Abstract: Bacteriophage O1 is a Myoviridae A1 group member used historically for identifying Salmonella. Sequencing revealed a single, linear, 86,155-base-pair genome with 39% average G+C content, 131 open reading frames, and 22 tRNAs. Closest protein homologs occur in Erwinia amylovora phage φEa21-4 and Escherichia coli phage wV8. Proteomic analysis indentified structural proteins: Gp23, Gp36 (major tail protein), Gp49, Gp53, Gp54, Gp55, Gp57, Gp58 (major capsid protein), Gp59, Gp63, Gp64, Gp67, Gp68, Gp69, Gp73, Gp74 and Gp77 (tail fiber). Based on phage-host codon differences, 7 tRNAs could affect translation rate during infection. Introns, holin-lysin cassettes, bacterial toxin homologs and host RNA polymerase-modifying genes were absent.
Keywords: Salmonella; bacteriophage; Myoviridae; Felix O1; DNA sequence; bioinformatics Salmonella; bacteriophage; Myoviridae; Felix O1; DNA sequence; bioinformatics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |

MDPI and ACS Style

Whichard, J.M.; Weigt, L.A.; Borris, D.J.; Li, L.L.; Zhang, Q.; Kapur, V.; Pierson, F.W.; Lingohr, E.J.; She, Y.-M.; Kropinski, A.M.; Sriranganathan, N. Complete Genomic Sequence of Bacteriophage Felix O1. Viruses 2010, 2, 710-730.

AMA Style

Whichard JM, Weigt LA, Borris DJ, Li LL, Zhang Q, Kapur V, Pierson FW, Lingohr EJ, She Y-M, Kropinski AM, Sriranganathan N. Complete Genomic Sequence of Bacteriophage Felix O1. Viruses. 2010; 2(3):710-730.

Chicago/Turabian Style

Whichard, Jean M.; Weigt, Lee A.; Borris, Douglas J.; Li, Ling Ling; Zhang, Qing; Kapur, Vivek; Pierson, F. William; Lingohr, Erika J.; She, Yi-Min; Kropinski, Andrew M.; Sriranganathan, Nammalwar. 2010. "Complete Genomic Sequence of Bacteriophage Felix O1." Viruses 2, no. 3: 710-730.

Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert