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Viruses 2018, 10(3), 120; doi:10.3390/v10030120

Bovine Vaccinia: Insights into the Disease in Cattle

Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil
Authors to whom correspondence should be addressed.
Received: 1 February 2018 / Revised: 2 March 2018 / Accepted: 6 March 2018 / Published: 9 March 2018
(This article belongs to the Special Issue Smallpox and Emerging Zoonotic Orthopoxviruses: What Is Coming Next?)
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Bovine vaccinia (BV), caused by Vaccinia virus (VACV), is a zoonosis characterized by exanthematous lesions in the teats of dairy cows and the hands of milkers and is an important public health issue. Severe VACV-induced lesions in the teats and udder of cows and buffaloes could lead to mastitis and other secondary infections, thereby reducing productivity and resulting in economic losses to the dairy industry. In Brazil, BV re-emerged in the late 1990s and is now endemic in most of the Brazilian territory. In the last 15 years, much effort has been made to know more about this disease and its epidemiology, etiologic agents, and interactions with the host and the environment. In this review, we describe the known dynamics of VACV infection in cattle and the viral shedding routes, as well as the relevance of BV for animal and public health. View Full-Text
Keywords: zoonosis; Vaccinia virus; bovine vaccinia; orthopoxvirus; veterinary; cattle; public health zoonosis; Vaccinia virus; bovine vaccinia; orthopoxvirus; veterinary; cattle; public health

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Matos, A.C.D.; Rehfeld, I.S.; Guedes, M.I.M.C.; Lobato, Z.I.P. Bovine Vaccinia: Insights into the Disease in Cattle. Viruses 2018, 10, 120.

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