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Viruses 2009, 1(2), 298-316; doi:10.3390/v1020298
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Viroid Pathogenicity: One Process, Many Faces

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Received: 14 July 2009 / Revised: 31 August 2009 / Accepted: 1 September 2009 / Published: 10 September 2009
(This article belongs to the Special Issue Subviral RNAs)
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Abstract

Despite the non-coding nature of their small RNA genomes, the visible symptoms of viroid infection resemble those associated with many plant virus diseases. Recent evidence indicates that viroid-derived small RNAs acting through host RNA silencing pathways play a key role in viroid pathogenicity. Host responses to viroid infection are complex, involving signaling cascades containing host-encoded protein kinases and crosstalk between hormonal and defense-signaling pathways. Studies of viroid-host interaction in the context of entire biochemical or developmental pathways are just beginning, and many working hypotheses have yet to be critically tested.
Keywords: viroid pathogenicity; RNA silencing; disease induction viroid pathogenicity; RNA silencing; disease induction
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Owens, R.A.; Hammond, R.W. Viroid Pathogenicity: One Process, Many Faces. Viruses 2009, 1, 298-316.

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