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Protein-Protein Interaction Analysis by Docking
Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, D-93053 Regensburg, Germany
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Received: 1 December 2008; in revised form: 19 January 2009 / Accepted: 27 February 2009 / Published: 10 March 2009
Abstract: Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms such as amino acid based pair-potentials. We show some early results that demonstrate the general applicability of our approach.
Keywords: protein-protein docking; verification of protein interactions; 3D protein structures
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Fink, F.; Ederer, S.; Gronwald, W. Protein-Protein Interaction Analysis by Docking. Algorithms 2009, 2, 429-436.
Fink F, Ederer S, Gronwald W. Protein-Protein Interaction Analysis by Docking. Algorithms. 2009; 2(1):429-436.
Fink, Florian; Ederer, Stephan; Gronwald, Wolfram. 2009. "Protein-Protein Interaction Analysis by Docking." Algorithms 2, no. 1: 429-436.