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Algorithms 2009, 2(1), 429-436; doi:10.3390/a2010429
Article

Protein-Protein Interaction Analysis by Docking

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Received: 1 December 2008 / Revised: 19 January 2009 / Accepted: 27 February 2009 / Published: 10 March 2009
(This article belongs to the Special Issue Algorithms and Molecular Sciences)
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Abstract

Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms such as amino acid based pair-potentials. We show some early results that demonstrate the general applicability of our approach.
Keywords: protein-protein docking; verification of protein interactions; 3D protein structures protein-protein docking; verification of protein interactions; 3D protein structures
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fink, F.; Ederer, S.; Gronwald, W. Protein-Protein Interaction Analysis by Docking. Algorithms 2009, 2, 429-436.

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