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Materials 2016, 9(5), 383; doi:10.3390/ma9050383

Nanoparticles for Control of Biofilms of Acinetobacter Species

1
Department of Microbiology, Savitribai Phule Pune University, Pune 411007, India
2
Department of Biochemistry, The Institute of Science, Mumbai 400032, India
3
Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431004, India
*
Author to whom correspondence should be addressed.
Academic Editor: Hideyuki Kanematsu
Received: 13 March 2016 / Revised: 9 May 2016 / Accepted: 10 May 2016 / Published: 18 May 2016
(This article belongs to the Special Issue Biofilm and Materials Science)
View Full-Text   |   Download PDF [2658 KB, uploaded 18 May 2016]   |  

Abstract

Biofilms are the cause of 80% of microbial infections. Acinetobacter species have emerged as multi- and pan-drug-resistant bacteria and pose a great threat to human health. These act as nosocomial pathogens and form excellent biofilms, both on biotic and abiotic surfaces, leading to severe infections and diseases. Various methods have been developed for treatment and control of Acinetobacter biofilm including photodynamic therapy, radioimmunotherapy, prophylactic vaccines and antimicrobial peptides. Nanotechnology, in the present scenario, offers a promising alternative. Nanomaterials possess unique properties, and multiple bactericidal mechanisms render them more effective than conventional drugs. This review intends to provide an overview of Acinetobacter biofilm and the significant role of various nanoparticles as anti-biofouling agents, surface-coating materials and drug-delivery vehicles for biofilm control and treatment of Acinetobacter infections. View Full-Text
Keywords: Acinetobacter; biofilm; drug resistance; nanoparticles; phage; anti-biofilm agent Acinetobacter; biofilm; drug resistance; nanoparticles; phage; anti-biofilm agent
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Singh, R.; Nadhe, S.; Wadhwani, S.; Shedbalkar, U.; Chopade, B.A. Nanoparticles for Control of Biofilms of Acinetobacter Species. Materials 2016, 9, 383.

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