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Materials 2016, 9(3), 149; doi:10.3390/ma9030149

Synthesis, Characterization and Cytotoxicity of Novel Multifunctional Fe3O4@SiO2@GdVO4:Dy3+ Core-Shell Nanocomposite as a Drug Carrier

College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China
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Author to whom correspondence should be addressed.
Academic Editor: Dusan Losic
Received: 22 January 2016 / Revised: 22 February 2016 / Accepted: 24 February 2016 / Published: 2 March 2016
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Abstract

In this study, multifunctional Fe3O4@SiO2@GdVO4:Dy3+ nanocomposites were successfully synthesized via a two-step method. Their structure, luminescence and magnetic properties were characterized by X-ray diffraction (XRD), scanning electronic microscope (SEM), transmission electron microscopy (TEM), photoluminescence (PL) spectra and vibrating sample magnetometer (VSM). The results indicated that the as-prepared multifunctional composites displayed a well-defined core-shell structure. The composites show spherical morphology with a size distribution of around 360 nm. Additionally, the composites exhibit high saturation magnetization (20.40 emu/g) and excellent luminescence properties. The inner Fe3O4 cores and the outer GdVO4:Dy3+ layers endow the composites with good responsive magnetic properties and strong fluorescent properties, which endow the nanoparticles with great potential applications in drug delivery, magnetic resonance imaging, and marking and separating of cells in vitro. View Full-Text
Keywords: Fe3O4@SiO2@GdVO4:Dy3+; nanocomposites; core-shell structure; magnetic property; luminescence property Fe3O4@SiO2@GdVO4:Dy3+; nanocomposites; core-shell structure; magnetic property; luminescence property
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Li, B.; Fan, H.; Zhao, Q.; Wang, C. Synthesis, Characterization and Cytotoxicity of Novel Multifunctional Fe3O4@SiO2@GdVO4:Dy3+ Core-Shell Nanocomposite as a Drug Carrier. Materials 2016, 9, 149.

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