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Materials 2014, 7(5), 3946-3955; doi:10.3390/ma7053946
Article

Antimicrobial Activity of Chitosan-Carbon Nanotube Hydrogels

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Received: 5 November 2013; in revised form: 2 December 2013 / Accepted: 7 May 2014 / Published: 19 May 2014
(This article belongs to the Special Issue Nanocomposites of Polymers and Inorganic Particles 2013)
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Abstract: In the present study, we have prepared chitosan-carbon nanotube (Chitosan-CNT) hydrogels by the freeze-lyophilization method and examined their antimicrobial activity. Different concentrations of CNT were used in the preparation of Chitosan-CNT hydrogels. These differently concentrated CNT hydrogels were chemically characterized using Fourier Transform-Infrared Spectroscopy, Scanning Electron Microscopy and Optical microscopy. The porosity of the hydrogels were found to be >94%. Dispersion of chitosan was observed in the CNT matrix by normal photography and optical microscopy. The addition of CNT in the composite scaffold significantly reduced the water uptake ability. In order to evaluate antimicrobial activity, the serial dilution method was used towards Staphylococcus aureus, Escherichia coli and Candida tropicalis. The composite Chitosan-CNT hydrogel showed greater antimicrobial activity with increasing CNT concentration, suggesting that Chitosan-CNT hydrogel scaffold will be a promising biomaterial in biomedical applications.
Keywords: marine biomaterials; tissue engineering; chitosan; carbon nanotube; antimicrobial activity marine biomaterials; tissue engineering; chitosan; carbon nanotube; antimicrobial activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Venkatesan, J.; Jayakumar, R.; Mohandas, A.; Bhatnagar, I.; Kim, S.-K. Antimicrobial Activity of Chitosan-Carbon Nanotube Hydrogels. Materials 2014, 7, 3946-3955.

AMA Style

Venkatesan J, Jayakumar R, Mohandas A, Bhatnagar I, Kim S-K. Antimicrobial Activity of Chitosan-Carbon Nanotube Hydrogels. Materials. 2014; 7(5):3946-3955.

Chicago/Turabian Style

Venkatesan, Jayachandran; Jayakumar, Rangasamy; Mohandas, Annapoorna; Bhatnagar, Ira; Kim, Se-Kwon. 2014. "Antimicrobial Activity of Chitosan-Carbon Nanotube Hydrogels." Materials 7, no. 5: 3946-3955.


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