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Materials 2014, 7(3), 1455-1472; doi:10.3390/ma7031455
Article

Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure

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Received: 17 November 2013; in revised form: 16 December 2013 / Accepted: 17 February 2014 / Published: 25 February 2014
(This article belongs to the Section Biomaterials)
View Full-Text   |   Download PDF [758 KB, uploaded 25 February 2014]
Abstract: The electroactivity of purine and pyrimidine bases is the most important property of nucleic acids that is very useful for determining oligonucleotides using square wave voltammetry. This study was focused on the electrochemical behavior of adenine-containing oligonucleotides before and after their isolation using paramagnetic particles. Two peaks were detected—peak A related to the reduction of adenine base and another peak B involved in the interactions between individual adenine strands and contributes to the formation of various spatial structures. The influence of the number of adenine bases in the strand in the isolation process using paramagnetic particles was investigated too.
Keywords: adenine; adenine interaction; magnetic beads; square wave voltammetry; aptamer; biosensor; nanobiotechnology adenine; adenine interaction; magnetic beads; square wave voltammetry; aptamer; biosensor; nanobiotechnology
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Kremplova, M.; Fialova, D.; Nejdl, L.; Hynek, D.; Trnkova, L.; Hubalek, J.; Kizek, R.; Adam, V. Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure. Materials 2014, 7, 1455-1472.

AMA Style

Kremplova M, Fialova D, Nejdl L, Hynek D, Trnkova L, Hubalek J, Kizek R, Adam V. Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure. Materials. 2014; 7(3):1455-1472.

Chicago/Turabian Style

Kremplova, Monika; Fialova, Dana; Nejdl, Lukas; Hynek, David; Trnkova, Libuse; Hubalek, Jaromir; Kizek, Rene; Adam, Vojtech. 2014. "Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure." Materials 7, no. 3: 1455-1472.


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