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Materials 2013, 6(3), 1090-1117; doi:10.3390/ma6031090
Article

Towards a Consensus View on Understanding Nanomaterials Hazards and Managing Exposure: Knowledge Gaps and Recommendations

1
, 2
, 3,4
, 5
, 6
, 7
, 8,9
, 10
 and 11,*
1 Centre for Bioethics & Emerging Technologies, St Mary's University College, London, TW1 4SX, UK 2 Centre for BioNano Interactions, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, UK 3 National Institute for Public Health and the Environment (RIVM), Bilthoven 3720 BA, The Netherlands 4 Institute for Risk Assessment Sciences, Utrecht University, NL-3508 TD Utrecht, The Netherlands 5 Ecotoxicology Research and Innovation Centre, The University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK 6 School of Life Sciences, Heriot-Watt University, Edinburgh EH14 4AS, UK 7 Institute for Occupational Safety and Health, Deutsche Gesetzliche Unfallversicherung (DGUV), Alte Heerstr 111, Sankt Augustin 53757, Germany 8 Air Quality & Sustainable Nanotechnology, Institute of Energy and Environmental Technology e.V. (IUTA), D-47229 Duisburg, Germany 9 Center for Nanointegration Duisburg-Essen (CeNIDE), University Duisburg-Essen, D-47057 Duisburg, Germany 10 Health Effects Laboratory, Environmental Chemistry Department, NILU-Norwegian Institute for Air Research, Instituttveien 18, Kjeller 2027, Norway 11 Institute for Work and Health, Rte de la Corniche 2, Epalinges-Lausanne CH-1066, Switzerland
* Author to whom correspondence should be addressed.
Received: 11 January 2013 / Revised: 21 February 2013 / Accepted: 28 February 2013 / Published: 20 March 2013
(This article belongs to the Special Issue Nanotoxicology)
Download PDF [122 KB, uploaded 20 March 2013]

Abstract

The aim of this article is to present an overview of salient issues of exposure, characterisation and hazard assessment of nanomaterials as they emerged from the consensus-building of experts undertaken within the four year European Commission coordination project NanoImpactNet. The approach adopted is to consolidate and condense the findings and problem-identification in such a way as to identify knowledge-gaps and generate a set of interim recommendations of use to industry, regulators, research bodies and funders. The categories of recommendation arising from the consensual view address: significant gaps in vital factual knowledge of exposure, characterisation and hazards; the development, dissemination and standardisation of appropriate laboratory protocols; address a wide range of technical issues in establishing an adequate risk assessment platform; the more efficient and coordinated gathering of basic data; greater inter-organisational cooperation; regulatory harmonization; the wider use of the life-cycle approaches; and the wider involvement of all stakeholders in the discussion and solution-finding efforts for nanosafety.
Keywords: nanomaterial characterisation; release; exposure; hazard; nanotoxicology; nanosafety; occupational health; consensus building; life cycle approach; monitoring; protocols nanomaterial characterisation; release; exposure; hazard; nanotoxicology; nanosafety; occupational health; consensus building; life cycle approach; monitoring; protocols
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Hunt, G.; Lynch, I.; Cassee, F.; Handy, R.D.; Fernandes, T.F.; Berges, M.; Kuhlbusch, T.A.J.; Dusinska, M.; Riediker, M. Towards a Consensus View on Understanding Nanomaterials Hazards and Managing Exposure: Knowledge Gaps and Recommendations. Materials 2013, 6, 1090-1117.

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