Materials 2013, 6(11), 5335-5351; doi:10.3390/ma6115335
Article

Phosphorus Effects of Mesoporous Bioactive Glass on Occlude Exposed Dentin

1 Advanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, College of Engineering, Feng Chia University, Taichung 40724, Taiwan 2 School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan 3 Department of Family Dentistry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan 4 Department of Fragrance and Cosmetic Science, Kaohsiung Medical University, Kaohsiung 80708, Taiwan 5 Department of Fragrance and Cosmetic Science, Kaohsiung Medical University, Kaohsiung 80708, Taiwan 6 Department of Orthopaedics, Chi Mei Foundation Hospital, Tainan 71004, Taiwan 7 Department of Electrical Engineering, Southern Taiwan University of Science and Technology, Tainan 71005, Taiwan These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 11 August 2013; in revised form: 11 October 2013 / Accepted: 14 November 2013 / Published: 19 November 2013
(This article belongs to the Special Issue Ceramics for Healthcare 2013)
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Abstract: In recent studies, sealing of exposed dentinal tubules is generally considered as one of the most effective strategies to treat dentin hypersensitivity. Mesoporous bioactive glass (MBG) is a potential material for treating dentin hypersensitivity due to its highly specific areas for dissolution and re-precipitated reaction for reduction in dentin permeability. The groups of commercial products of PerioGlas®, synthetic MBG and MBG without phosphorus (MBGNP) were compared. The MBG and MBGNP powders were prepared by the sol-gel method and mixed with different calculated ratios of phosphoric acid (PA) and then was brushed onto dentin surfaces. We used X-ray diffractometer (XRD), scanning electronic microscope (SEM), and Fourier transform infrared spectroscopy (FTIR) to investigate the physiochemistry and the occlusion ability of dentinal tubules. The results showed that MBG paste mixed with PA solution has a better ability for occluding dentinal tubules than MBGNP; it has a short reaction time and good operability. The major crystallite phase of MBG agents was monocalcium phosphate monohydrate [Ca(H2PO4)2·H2O] in the early stages of the reactions. MBG pastes that were mixed with 30% and 40% PA had the ability to create excellent penetration depth greater than 80 μm. These agents have the potential to treat dentin hypersensitivity.
Keywords: mesoporous bioactive glass; phosphoric acid; dentin hypersensitivity

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MDPI and ACS Style

Chen, W.-C.; Chen, C.-H.; Kung, J.-C.; Hsiao, Y.-C.; Shih, C.-J.; Chien, C.-S. Phosphorus Effects of Mesoporous Bioactive Glass on Occlude Exposed Dentin. Materials 2013, 6, 5335-5351.

AMA Style

Chen W-C, Chen C-H, Kung J-C, Hsiao Y-C, Shih C-J, Chien C-S. Phosphorus Effects of Mesoporous Bioactive Glass on Occlude Exposed Dentin. Materials. 2013; 6(11):5335-5351.

Chicago/Turabian Style

Chen, Wen-Cheng; Chen, Cheng-Hwei; Kung, Jung-Chang; Hsiao, Yu-Cheng; Shih, Chi-Jen; Chien, Chi-Sheng. 2013. "Phosphorus Effects of Mesoporous Bioactive Glass on Occlude Exposed Dentin." Materials 6, no. 11: 5335-5351.

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