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Calcium Orthophosphate-Based Bioceramics
Materials 2013, 6(11), 5335-5351; doi:10.3390/ma6115335

Phosphorus Effects of Mesoporous Bioactive Glass on Occlude Exposed Dentin

5,*  and 6,7,*
Received: 11 August 2013 / Revised: 11 October 2013 / Accepted: 14 November 2013 / Published: 19 November 2013
(This article belongs to the Special Issue Ceramics for Healthcare 2013)
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In recent studies, sealing of exposed dentinal tubules is generally considered as one of the most effective strategies to treat dentin hypersensitivity. Mesoporous bioactive glass (MBG) is a potential material for treating dentin hypersensitivity due to its highly specific areas for dissolution and re-precipitated reaction for reduction in dentin permeability. The groups of commercial products of PerioGlas®, synthetic MBG and MBG without phosphorus (MBGNP) were compared. The MBG and MBGNP powders were prepared by the sol-gel method and mixed with different calculated ratios of phosphoric acid (PA) and then was brushed onto dentin surfaces. We used X-ray diffractometer (XRD), scanning electronic microscope (SEM), and Fourier transform infrared spectroscopy (FTIR) to investigate the physiochemistry and the occlusion ability of dentinal tubules. The results showed that MBG paste mixed with PA solution has a better ability for occluding dentinal tubules than MBGNP; it has a short reaction time and good operability. The major crystallite phase of MBG agents was monocalcium phosphate monohydrate [Ca(H2PO4)2·H2O] in the early stages of the reactions. MBG pastes that were mixed with 30% and 40% PA had the ability to create excellent penetration depth greater than 80 μm. These agents have the potential to treat dentin hypersensitivity.
Keywords: mesoporous bioactive glass; phosphoric acid; dentin hypersensitivity mesoporous bioactive glass; phosphoric acid; dentin hypersensitivity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Chen, W.-C.; Chen, C.-H.; Kung, J.-C.; Hsiao, Y.-C.; Shih, C.-J.; Chien, C.-S. Phosphorus Effects of Mesoporous Bioactive Glass on Occlude Exposed Dentin. Materials 2013, 6, 5335-5351.

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