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Materials 2012, 5(2), 350-363; doi:10.3390/ma5020350

Carbon Nanomaterials: Efficacy and Safety for Nanomedicine

1
Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan
2
Laboratory of Biopharmaceutical Research, National Institute of Biomedical Innovation, 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan
3
The Center for Advanced Medical Engineering and Informatics, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan
4
Laboratory of Biomedical Innovation, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan
*
Authors to whom correspondence should be addressed.
Received: 16 December 2011 / Revised: 11 February 2012 / Accepted: 15 February 2012 / Published: 21 February 2012
(This article belongs to the Special Issue Carbon Nanotubes: Synthesis, Characterization and Applications)
View Full-Text   |   Download PDF [124 KB, uploaded 21 February 2012]

Abstract

Carbon nanomaterials, including fullerenes, carbon nanohorns, and carbon nanotubes, are increasingly being used in various fields owing to these materials’ unique, size-dependent functions and physicochemical properties. Recently, because of their high variability and stability, carbon nanomaterials have been explored as a novel tool for the delivery of therapeutic molecules including peptide and nucleic acid cancer drugs. However, insufficient information is available regarding the safety of carbon nanomaterials for human health, even though such information is vital for the development of safe and effective nanomedicine technologies. In this review, we discuss currently available information regarding the safety of carbon nanomaterials in nanomedicine applications, including information obtained from our own studies; and we discuss types of carbon nanomaterials that demonstrate particular promise for safe nanomedicine technologies. View Full-Text
Keywords: nanomedicine; carbon nanomaterials; fullerenes; carbon nanohorns; carbon nanotubes; drug delivery; nano safety science nanomedicine; carbon nanomaterials; fullerenes; carbon nanohorns; carbon nanotubes; drug delivery; nano safety science
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Yamashita, T.; Yamashita, K.; Nabeshi, H.; Yoshikawa, T.; Yoshioka, Y.; Tsunoda, S.-I.; Tsutsumi, Y. Carbon Nanomaterials: Efficacy and Safety for Nanomedicine. Materials 2012, 5, 350-363.

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