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Materials 2012, 5(11), 2292-2305; doi:10.3390/ma5112292
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Cell-Sized Liposomes and Droplets: Real-World Modeling of Living Cells

1,*  and 2,*
Received: 18 October 2012 / Revised: 8 November 2012 / Accepted: 8 November 2012 / Published: 13 November 2012
(This article belongs to the Special Issue Supported Lipid Membranes)
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Abstract

Recent developments in studies concerning cell-sized vesicles, such as liposomes with a lipid bilayer and water-in-oil droplets covered by a lipid monolayer, aim to realize the real-world modeling of living cells. Compartmentalization with a membrane boundary is essential for the organization of living systems. Due to the relatively large surface/volume ratio in microconfinement, the membrane interface influences phenomena related to biological functions. In this article, we mainly focus on the following subjects: (i) conformational transition of biopolymers in a confined space; (ii) molecular association on the membrane surface; and (iii) remote control of cell-sized membrane morphology.
Keywords: liposome; droplet; cell-sized confinement; lipid membrane; DNA; compartmentalization; nanoparticle liposome; droplet; cell-sized confinement; lipid membrane; DNA; compartmentalization; nanoparticle
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Hamada, T.; Yoshikawa, K. Cell-Sized Liposomes and Droplets: Real-World Modeling of Living Cells. Materials 2012, 5, 2292-2305.

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