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• Slenters, T
• Fromm, K
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• Fromm, K
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• Slenters, T
• Fromm, K

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Materials 2011, 4(2), 355-367; doi:10.3390/ma4020355

Article

In vitro Biocompatibility of New Silver(I) Coordination Compound Coated-Surfaces for Dental Implant Applications

Priscilla S. Brunetto, Tünde Vig Slenters and Katharina M. Fromm*

University of Fribourg, Department of Chemistry, Chemin du Musée 9, CH-1700 Fribourg, Switzerland

* Author to whom correspondence should be addressed.

Received: 4 January 2011; in revised form: 19 January 2011 / Accepted: 24 January 2011 / Published: 28 January 2011

(This article belongs to the Special Issue Dental Biomaterials)

Download PDF Full-Text [1809 KB, uploaded 31 January 2011 17:15 CET]

Abstract: Biofilm formation on implant materials causes a common problem: resistance to aggressive pharmacological agents as well as host defenses. Therefore, to reduce bacterial adhesion to implant surfaces we propose to use silver(I) coordination networks as it is known that silver is the most powerful antimicrobial inorganic agent. As a model surface, self-assembled monolayers (SAMs) on gold Au(111) was used to permit permanent attachment of our silver(I) coordination networks. The surface coatings showed typical nano-structured surfaces with a good biocompatibility for soft-tissue integration with fibroblast cells.

Keywords: silver; cytotoxicity; biocompatibility

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