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Materials 2010, 3(3), 1913-1927; doi:10.3390/ma3031913

Freeze-Casting of Porous Biomaterials: Structure, Properties and Opportunities

Laboratoire de Synthèse et Fonctionnalisation des Céramiques, UMR 3080, CNRS/Saint-Gobain CREE, Cavaillon, France
Received: 5 February 2010 / Revised: 24 February 2010 / Accepted: 16 March 2010 / Published: 17 March 2010
(This article belongs to the Special Issue Ceramics for Healthcare)
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The freeze-casting of porous materials has received a great deal of attention during the past few years. This simple process, where a material suspension is simply frozen and then sublimated, provides materials with unique porous architectures, where the porosity is almost a direct replica of the frozen solvent crystals. This review focuses on the recent results on the process and the derived porous structures with regards to the biomaterials applications. Of particular interest is the architecture of the materials and the versatility of the process, which can be readily controlled and applied to biomaterials applications. A careful control of the starting formulation and processing conditions is required to control the integrity of the structure and resulting properties. Further in vitro and in vivo investigations are required to validate the potential of this new class of porous materials.
Keywords: freeze-casting; porous ceramics; composites; biomaterials freeze-casting; porous ceramics; composites; biomaterials
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Deville, S. Freeze-Casting of Porous Biomaterials: Structure, Properties and Opportunities. Materials 2010, 3, 1913-1927.

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