Materials 2010, 3(3), 1803-1832; doi:10.3390/ma3031803
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Surface Engineering and Patterning Using Parylene for Biological Applications

1,2email and 2,* email
Received: 1 February 2010; Accepted: 11 March 2010 / Published: 15 March 2010
(This article belongs to the Special Issue Advances in Biomaterials)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Parylene is a family of chemically vapour deposited polymer with material properties that are attractive for biomedicine and nanobiotechnology. Chemically inert parylene “peel-off” stencils have been demonstrated for micropatterning biomolecular arrays with high uniformity, precise spatial control down to nanoscale resolution. Such micropatterned surfaces are beneficial in engineering biosensors and biological microenvironments. A variety of substituted precursors enables direct coating of functionalised parylenes onto biomedical implants and microfluidics, providing a convenient method for designing biocompatible and bioactive surfaces. This article will review the emerging role and applications of parylene as a biomaterial for surface chemical modification and provide a future outlook.
Keywords: parylene; micropatterning; surface modification; [2.2]paracyclophane; biomaterial; bioactive; biomolecular; nanobiotechnology; microarray; microfluidic
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MDPI and ACS Style

Tan, C.P.; Craighead, H.G. Surface Engineering and Patterning Using Parylene for Biological Applications. Materials 2010, 3, 1803-1832.

AMA Style

Tan CP, Craighead HG. Surface Engineering and Patterning Using Parylene for Biological Applications. Materials. 2010; 3(3):1803-1832.

Chicago/Turabian Style

Tan, Christine P.; Craighead, Harold G. 2010. "Surface Engineering and Patterning Using Parylene for Biological Applications." Materials 3, no. 3: 1803-1832.

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