Materials 2009, 2(3), 945-957; doi:10.3390/ma2030945
Article

Biocompatibility of Collagen Membranes Assessed by Culturing Human J111 Macrophage Cells

1email, 2email, 2email, 2email and 2,* email
Received: 29 June 2009; in revised form: 4 August 2009 / Accepted: 14 August 2009 / Published: 18 August 2009
(This article belongs to the Special Issue Biocompatibility of Materials)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: We have carried out an in vitro study on the interactions of human macrophages (J111 cell line) with different scaffolds made of type I and II collagen, isolated from horse tendon and from horse articular and trachea cartilage, in order to assess growth properties and biocompatibility of these membranes. We have therefore evaluated cell adhesion and proliferation as well as cytokine production considered an indicator of macrophage activation. The inflammatory response is in fact one of the major causes of collagen destruction thus interfering with cell and tissue behaviour. Moreover, the morphology of cells, seeded on membranes selected for the best characteristics, was described. Results might be relevant for in vivo application such ad “tissue engineering” and/or specialized cells implants.
Keywords: collagen membrane; cell culture; proliferation; cytokine production
PDF Full-text Download PDF Full-Text [1040 KB, uploaded 17 August 2009 23:27 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Aruta, C.G.; Croce, M.A.; Quaglino, D.; Guerra, D.; Tiozzo, R. Biocompatibility of Collagen Membranes Assessed by Culturing Human J111 Macrophage Cells. Materials 2009, 2, 945-957.

AMA Style

Aruta CG, Croce MA, Quaglino D, Guerra D, Tiozzo R. Biocompatibility of Collagen Membranes Assessed by Culturing Human J111 Macrophage Cells. Materials. 2009; 2(3):945-957.

Chicago/Turabian Style

Aruta, Claudia G.; Croce, Maria A.; Quaglino, Daniela; Guerra, Deanna; Tiozzo, Roberta. 2009. "Biocompatibility of Collagen Membranes Assessed by Culturing Human J111 Macrophage Cells." Materials 2, no. 3: 945-957.


Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert