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Materials 2017, 10(7), 719; doi:10.3390/ma10070719

Design and Production of Continuously Gradient Macro/Microporous Calcium Phosphate (CaP) Scaffolds Using Ceramic/Camphene-Based 3D Extrusion

Department of Biomedical Engineering, Korea University, Seoul 136-701, Korea
Department of Materials Science and Engineering, Seoul National University, Seoul 151-742, Korea
Author to whom correspondence should be addressed.
Received: 24 May 2017 / Revised: 18 June 2017 / Accepted: 24 June 2017 / Published: 28 June 2017
(This article belongs to the Section Biomaterials)
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This study proposes a new type of calcium phosphate (CaP) scaffolds with a continuously gradient macro/microporous structure using the ceramic/camphene-based 3D extrusion process. Green filaments with a continuously gradient core/shell structure were successfully produced by extruding a bilayered feedrod comprised of a CaP/camphene mixture lower part and a pure camphene upper part. The extruded filaments were then deposited in a controlled manner to construct triangular prisms, followed by the assembly process for the production of CaP scaffolds with a gradient core/shell structure. In addition, a gradient microporous structure was created by heat-treating the green body at 43 °C to induce the overgrowth of camphene dendrites in the CaP/camphene walls. The produced CaP scaffold showed a highly macroporous structure within its inner core, where the size of macrochannels increased gradually with an increase in the distance from the outer shell, while relatively larger micropores were created in the outer shell. View Full-Text
Keywords: additive manufacturing; extrusion; porous ceramics; biomedical applications additive manufacturing; extrusion; porous ceramics; biomedical applications

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Ahn, M.-K.; Moon, Y.-W.; Maeng, W.-Y.; Koh, Y.-H.; Kim, H.-E. Design and Production of Continuously Gradient Macro/Microporous Calcium Phosphate (CaP) Scaffolds Using Ceramic/Camphene-Based 3D Extrusion. Materials 2017, 10, 719.

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