Next Article in Journal
Low-Temperature, Solution-Processed, Transparent Zinc Oxide-Based Thin-Film Transistors for Sensing Various Solvents
Previous Article in Journal
Lattice Modeling of Early-Age Behavior of Structural Concrete
Previous Article in Special Issue
Boronic Acid as Glucose-Sensitive Agent Regulates Drug Delivery for Diabetes Treatment
Article Menu
Issue 3 (March) cover image

Export Article

Open AccessReview
Materials 2017, 10(3), 232; doi:10.3390/ma10030232

Advances in the Fabrication of Antimicrobial Hydrogels for Biomedical Applications

1
Departamento de Química, Matemáticas y del Medio Ambiente, Facultad de Ciencias Naturales, Universidad Tecnológica Metropolitana, P.O. Box 9845, Correo 21, Santiago 7800003, Chile
2
Departamento de Ingeniería Estructural y Geotecnia, Escuela de Ingeniería, Pontificia Universidad Católica de Chile, P.O. Box 306, Correo 22, Santiago 7820436, Chile
3
Departamento de Química y Propiedades de Polímeros, Instituto de Ciencia y Tecnología de Polímeros-Consejo Superior de Investigaciones Científicas (ICTP-CSIC), Juan de la Cierva 3, Madrid 28006, Spain
*
Author to whom correspondence should be addressed.
Academic Editors: Jie Zheng, Yuping Bao and John Zhanhu Guo
Received: 3 January 2017 / Revised: 7 February 2017 / Accepted: 20 February 2017 / Published: 26 February 2017
(This article belongs to the Special Issue Smart Biomaterials and Biointerfaces)
View Full-Text   |   Download PDF [8165 KB, uploaded 27 February 2017]   |  

Abstract

This review describes, in an organized manner, the recent developments in the elaboration of hydrogels that possess antimicrobial activity. The fabrication of antibacterial hydrogels for biomedical applications that permits cell adhesion and proliferation still remains as an interesting challenge, in particular for tissue engineering applications. In this context, a large number of studies has been carried out in the design of hydrogels that serve as support for antimicrobial agents (nanoparticles, antibiotics, etc.). Another interesting approach is to use polymers with inherent antimicrobial activity provided by functional groups contained in their structures, such as quaternary ammonium salt or hydrogels fabricated from antimicrobial peptides (AMPs) or natural polymers, such as chitosan. A summary of the different alternatives employed for this purpose is described in this review, considering their advantages and disadvantages. Finally, more recent methodologies that lead to more sophisticated hydrogels that are able to react to external stimuli are equally depicted in this review. View Full-Text
Keywords: hydrogels; antimicrobial activity; antimicrobial agents; chitosan; silver nanoparticles hydrogels; antimicrobial activity; antimicrobial agents; chitosan; silver nanoparticles
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

González-Henríquez, C.M.; Sarabia-Vallejos, M.A.; Rodriguez-Hernandez, J. Advances in the Fabrication of Antimicrobial Hydrogels for Biomedical Applications. Materials 2017, 10, 232.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top