In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste
AbstractIntroduction: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. Methods: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate® Pro-Relief™ paste, CLP paste, and double distilled water (ddH2O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment. One-way ANOVA and post-hoc Tukey’s test were used to determine whether there were any statistically significant differences in dentinal tubule diameter. Results: A significant decrease occurred in the mean tubule diameter for dentin disks treated with CLP paste. A decrease was observed from 3.52 ± 0.83 µm to 2.62 ± 0.42 µm right after treatment, further decreasing to 1.71 ± 0.45 µm after immersion in artificial saliva for 14 days (p < 0.05). Conclusions: The results suggest that the CLP based desensitizing paste has remineralization properties and provides instant and lasting effectiveness in dentinal tubule occlusion. View Full-Text
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Yang, J.-C.; Hu, H.-T.; Lee, S.-Y.; Hsieh, S.-C.; Huang, P.-C.; Ma, C.-F.; Ji, D.-Y.; Chang, L.-Y.; Teng, N.-C. In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste. Materials 2017, 10, 228.
Yang J-C, Hu H-T, Lee S-Y, Hsieh S-C, Huang P-C, Ma C-F, Ji D-Y, Chang L-Y, Teng N-C. In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste. Materials. 2017; 10(3):228.Chicago/Turabian Style
Yang, Jen-Chang; Hu, Hsin-Tai; Lee, Sheng-Yang; Hsieh, Sung-Chih; Huang, Pei-Chi; Ma, Chen-Feng; Ji, Dian-Yu; Chang, Liang-Yu; Teng, Nai-Chia. 2017. "In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste." Materials 10, no. 3: 228.
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