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Int. J. Environ. Res. Public Health 2012, 9(3), 868-879; doi:10.3390/ijerph9030868
Article

Assessment of Exposure to Alcohol Vapor from Alcohol-Based Hand Rubs

 and *
Received: 16 February 2012; in revised form: 6 March 2012 / Accepted: 7 March 2012 / Published: 13 March 2012
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Abstract: This study assessed the inhaled dose of alcohol during hand disinfection. Experiments were conducted with two types of hand rub using two hand disinfection procedures. Air samples were collected every 10 s from the breathing zone, by bubbling through a mixture of K2Cr2O7 and H2SO4. The reduction of dichromate ions in the presence of alcohols was followed by UV-vis spectrophotometry. The difference in intensity of the dichromate absorption peak was used to quantify the alcohol concentration expressed in ethanol equivalent. During hygienic hand disinfection, the mean ethanol equivalent concentrations peaked at around 20–30 s for both hand rubs (14.3 ± 1.4 mg/L for hand rub 1 and 13.2 ± 0.7 mg/L for hand rub 2). During surgical hand disinfection, two peaks were found at the same time (40 and 80 s) for both hand rubs. The highest mean concentrations were 20.2 ± 0.9 mg/L for hand rub 1 and 18.1 ± 0.9 mg/L for hand rub 2. For hand rub 1, the total absorbed doses, calculated from ethanol with an inhalation flow of 24 L/min and an absorption rate of 62%, were 46.5 mg after one hygienic hand disinfection and 203.9 mg after one surgical hand disinfection. Although the use of ABHRs leads to the absorption of very low doses, sudden, repeated inhalation of high alcohol concentrations raises the question of possible adverse health effects.
Keywords: inhalation exposure; alcohol-based hand rubs; passive alcoholization; healthcare workers; UV-visible spectrophotometry inhalation exposure; alcohol-based hand rubs; passive alcoholization; healthcare workers; UV-visible spectrophotometry
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Bessonneau, V.; Thomas, O. Assessment of Exposure to Alcohol Vapor from Alcohol-Based Hand Rubs. Int. J. Environ. Res. Public Health 2012, 9, 868-879.

AMA Style

Bessonneau V, Thomas O. Assessment of Exposure to Alcohol Vapor from Alcohol-Based Hand Rubs. International Journal of Environmental Research and Public Health. 2012; 9(3):868-879.

Chicago/Turabian Style

Bessonneau, Vincent; Thomas, Olivier. 2012. "Assessment of Exposure to Alcohol Vapor from Alcohol-Based Hand Rubs." Int. J. Environ. Res. Public Health 9, no. 3: 868-879.


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