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Int. J. Environ. Res. Public Health 2011, 8(7), 2747-2757; doi:10.3390/ijerph8072747
Review

Genetic Risk for Alcoholic Chronic Pancreatitis

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Received: 7 June 2011 / Accepted: 20 June 2011 / Published: 30 June 2011
(This article belongs to the Special Issue Alcohol and Public Health)
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Abstract

In recent years many studies have examined the genetic predisposition to pancreatic diseases. Pancreatic disease of an alcoholic etiology was determined to be a multi-factorial disease, where environmental factors interact with the genetic profile of the individual. In this review we discuss the main results from studies examining the frequency of genetic mutations in alcoholic chronic pancreatitis.
Keywords: pancreatic diseases; alcoholism; genetics; cationic trypsinogen; cystic fibrosis transmembrane conductance regulator; serine protease inhibitor kazal type 1; chymotrypsin C pancreatic diseases; alcoholism; genetics; cationic trypsinogen; cystic fibrosis transmembrane conductance regulator; serine protease inhibitor kazal type 1; chymotrypsin C
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Zadrozny Gouvêa da Costa, M.; Guarita, D.R.; Ono-Nita, S.K.; Paranaguá-Vezozzo, D.C.; Gonçalves Felga, G.E.; Arcon Pedroso, M.R.; Souza, M.M.T.; Nasser, P.D.; Da Silva Ferreira, C.; Carrilho, F.J. Genetic Risk for Alcoholic Chronic Pancreatitis. Int. J. Environ. Res. Public Health 2011, 8, 2747-2757.

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