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Int. J. Environ. Res. Public Health 2010, 7(4), 1486-1499; doi:10.3390/ijerph7041486

Air Pollution Exposure—A Trigger for Myocardial Infarction?

1
Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden
2
Bristol-Myers Squibb Research and Development, Pennington, NJ 08534, USA
3
Department of Cardiology, Karolinska Institutet, Stockholm South Hospital, SE-118 83 Stockholm, Sweden
4
Department of Public Health Sciences, Karolinska Institutet, SE-171 77 Stockholm, Sweden
5
Department of Public Health and Caring Sciences, Uppsala University, SE-751 22 Uppsala, Sweden
6
AstraZeneca R&D, SE-431 83 Mölndal, Sweden
*
Author to whom correspondence should be addressed.
Received: 18 January 2010 / Revised: 26 March 2010 / Accepted: 28 March 2010 / Published: 31 March 2010
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Abstract

The association between ambient air pollution exposure and hospitalization for cardiovascular events has been reported in several studies with conflicting results. A case-crossover design was used to investigate the effects of air pollution in 660 first-time myocardial infarction cases in Stockholm in 1993–1994, interviewed shortly after diagnosis using a standard protocol. Air pollution data came from central urban background monitors. No associations were observed between the risk for onset of myocardial infarction and two-hour or 24-hour air pollution exposure. No evidence of susceptible subgroups was found. This study provides no support that moderately elevated air pollution levels trigger first-time myocardial infarction. View Full-Text
Keywords: air pollution; myocardial infarction; trigger; onset; case cross-over design air pollution; myocardial infarction; trigger; onset; case cross-over design
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Berglind, N.; Ljungman, P.; Möller, J.; Hallqvist, J.; Nyberg, F.; Rosenqvist, M.; Pershagen, G.; Bellander, T. Air Pollution Exposure—A Trigger for Myocardial Infarction? Int. J. Environ. Res. Public Health 2010, 7, 1486-1499.

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