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Int. J. Environ. Res. Public Health 2010, 7(3), 842-852; doi:10.3390/ijerph7030842
Article

Waist Circumference and BMI in Relation to Serum High Sensitivity C-Reactive Protein (hs-CRP) in Cuban Americans With and Without Type 2 Diabetes

1,* , 1
, 1
 and 2
1 Department of Dietetics & Nutrition, Florida International University, 11200 S.W. 8th Street, Miami, FL 33199, USA 2 Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
* Author to whom correspondence should be addressed.
Received: 10 February 2010 / Accepted: 4 March 2010 / Published: 8 March 2010
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Abstract

Relationship between high-sensitivity C-reactive protein (hs-CRP) and adiposity by diabetes status and gender in Cuban-Americans with and without type 2 diabetes (T2D) was studied. Adult subjects, 226 females, 129 males participated in a case control, single time point study. Subjects with T2D were older, had higher waist circumference (WC) and body mass index (BMI). WC and BMI were associated with ln hs-CRP (P < 0.001). An interaction with diabetes status was found for BMI (P = 0.037). Gender showed a strong relationship with ln hs-CRP (P < 0.001), which was moderated by diabetes status. Only males without diabetes exhibited a significant relationship for both WC and BMI with ln hs-CRP. In this sample of Cuban-Americans, WC and BMI had stronger associations with ln hs-CRP but not with diabetes status. Obesity prevention and controlling for CRP levels may be necessary to eliminate its contributions to develop diabetes and cardiovascular disease (CVD).
Keywords: Type 2 diabetes; high-sensitivity C-reactive protein; waist circumference; body mass index Type 2 diabetes; high-sensitivity C-reactive protein; waist circumference; body mass index
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Huffman, F.G.; Whisner, S.; Zarini, G.G.; Nath, S. Waist Circumference and BMI in Relation to Serum High Sensitivity C-Reactive Protein (hs-CRP) in Cuban Americans With and Without Type 2 Diabetes. Int. J. Environ. Res. Public Health 2010, 7, 842-852.

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