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Int. J. Environ. Res. Public Health 2009, 6(9), 2426-2435; doi:10.3390/ijerph6092426

Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study

Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
* Author to whom correspondence should be addressed.
Received: 11 August 2009 / Accepted: 4 September 2009 / Published: 10 September 2009
(This article belongs to the Special Issue Alcohol and Public Health)
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This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3–6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.
Keywords: alcohol; ARDS; population alcohol; ARDS; population
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Thakur, L.; Kojicic, M.; Thakur, S.J.; Pieper, M.S.; Kashyap, R.; Trillo-Alvarez, C.A.; Javier, F.; Cartin-Ceba, R.; Gajic, O. Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study. Int. J. Environ. Res. Public Health 2009, 6, 2426-2435.

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