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Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study
Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
* Author to whom correspondence should be addressed.
Received: 11 August 2009; Accepted: 4 September 2009 / Published: 10 September 2009
Abstract: This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3–6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.
Keywords: alcohol; ARDS; population
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MDPI and ACS Style
Thakur, L.; Kojicic, M.; Thakur, S.J.; Pieper, M.S.; Kashyap, R.; Trillo-Alvarez, C.A.; Javier, F.; Cartin-Ceba, R.; Gajic, O. Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study. Int. J. Environ. Res. Public Health 2009, 6, 2426-2435.
Thakur L, Kojicic M, Thakur SJ, Pieper MS, Kashyap R, Trillo-Alvarez CA, Javier F, Cartin-Ceba R, Gajic O. Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study. International Journal of Environmental Research and Public Health. 2009; 6(9):2426-2435.
Thakur, Lokendra; Kojicic, Marija; Thakur, Sweta J.; Pieper, Matthew S.; Kashyap, Rahul; Trillo-Alvarez, Cesar A.; Javier, Fernandez; Cartin-Ceba, Rodrigo; Gajic, Ognjen. 2009. "Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study." Int. J. Environ. Res. Public Health 6, no. 9: 2426-2435.