Int. J. Environ. Res. Public Health 2009, 6(10), 2526-2533; doi:10.3390/ijerph6102526
Article

Epidemiological Study of Rickettsial Infections in Patients with Hypertransaminemia in Madrid (Spain)

Lourdes Lledó 1,* email, Rosario González 1,2 email, María Isabel Gegúndez 1 email, María Beltrán 1,2 email and José Vicente Saz 1 email
1 Department of Microbiology and Parasitology, Faculty of Medicine, University of Alcalá, Ctra. Madrid-Barcelona Km 33.6, Alcalá de Henares 28871, Spain 2 Department of Microbiology, Hospital “Príncipe de Asturias”, Ctra. Madrid-Barcelona Km 33.6, Alcalá de Henares 28871, Spain
* Author to whom correspondence should be addressed.
Received: 19 August 2009 / Accepted: 23 September 2009 / Published: 28 September 2009
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Abstract: A retrospective analysis was performed to detect anti-rickettsial antibodies in the serum of patients with hypertransaminemia of unknown etiology, and in that of healthy members of the general population of Madrid (Spain). Among 143 patients 16 (11.2%) were positive for anti-R. conorii IgG antibodies and 7% for R. typhi. PCR analysis was performed in patients with IgM antibodies. Among 143 healthy subjects from the general population, seven (4.9%) were positive for anti-R. conorii IgG antibodies, and 2.8% for R. typhi. These results show that anti-rickettsial antibodies are more commonly detected in patients with hypertransaminemia than in healthy people.
Keywords: Rickettsiae; hypertransaminemia; liver dysfunction; prevalence; Spain

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MDPI and ACS Style

Lledó, L.; González, R.; Gegúndez, M.I.; Beltrán, M.; Saz, J.V. Epidemiological Study of Rickettsial Infections in Patients with Hypertransaminemia in Madrid (Spain). Int. J. Environ. Res. Public Health 2009, 6, 2526-2533.

AMA Style

Lledó L, González R, Gegúndez MI, Beltrán M, Saz JV. Epidemiological Study of Rickettsial Infections in Patients with Hypertransaminemia in Madrid (Spain). International Journal of Environmental Research and Public Health. 2009; 6(10):2526-2533.

Chicago/Turabian Style

Lledó, Lourdes; González, Rosario; Gegúndez, María I.; Beltrán, María; Saz, José V. 2009. "Epidemiological Study of Rickettsial Infections in Patients with Hypertransaminemia in Madrid (Spain)." Int. J. Environ. Res. Public Health 6, no. 10: 2526-2533.

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