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Int. J. Environ. Res. Public Health 2017, 14(11), 1381; doi:10.3390/ijerph14111381

The Interaction between Ambient PM10 and NO2 on Mortality in Guangzhou, China

1
Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
2
Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China
*
Author to whom correspondence should be addressed.
Received: 7 October 2017 / Revised: 3 November 2017 / Accepted: 8 November 2017 / Published: 13 November 2017
(This article belongs to the Section Environmental Health)
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Abstract

Air pollution is now a significant environmental issue in China. To better understand the health impacts of ambient air pollution, this study investigated the potential interaction between PM10 and NO2 on mortality in Guangzhou, China. Time series data of daily non-accidental mortality and concentrations of PM10 and NO2 from 2006 to 2010 were collected. Based on generalized additive model, we developed two models (bivariate model and stratified model) to explore the interaction both qualitatively and quantitatively. At lag of 0–2 days, greater interactive effects between PM10 and NO2 were presented in the graphs. Positive modified effects were also found between the two pollutants on total non-accidental death and cardiovascular death. When the NO2 concentration was at a high level (>76.14 μg/m3), PM10 showed the greatest excess relative risk percentage (ERR%) for total non-accidental mortality (0.46, 95% CI: 0.13–0.79) and cardiovascular disease mortality (0.61, 95% CI: 0.06–1.16) for each 10 μg/m3 increase. During the period of high PM10 concentration (>89.82 μg/m3), NO2 demonstrated its strongest effect for total non-accidental mortality (ERR%: 0.92, 95% CI: 0.42–1.42) and cardiovascular disease mortality (ERR%: 1.20, 95% CI: 0.38–2.03). Our results suggest a positive interaction between PM10 and NO2 on non-accidental mortality in Guangzhou. View Full-Text
Keywords: air pollution; interaction; mortality; Guangzhou; generalized additive model air pollution; interaction; mortality; Guangzhou; generalized additive model
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Gu, Y.; Lin, H.; Liu, T.; Xiao, J.; Zeng, W.; Li, Z.; Lv, X.; Ma, W. The Interaction between Ambient PM10 and NO2 on Mortality in Guangzhou, China. Int. J. Environ. Res. Public Health 2017, 14, 1381.

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