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Int. J. Environ. Res. Public Health 2016, 13(5), 498; doi:10.3390/ijerph13050498

Brazilian Green Propolis Improves Antioxidant Function in Patients with Type 2 Diabetes Mellitus

1
Department of Nutrition, Tianjin Institute of Health and Environmental Medicine, Tianjin 300050, China
2
Department of Nutrition, Pingjin Hospital, Tianjin 300162, China
3
Department of Endocrinology, Pingjin Hospital, Tianjin 300162, China
4
Department of Health Education, Tianjin Institute of Health Education, Tianjin 300011, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Omorogieva Ojo
Received: 23 March 2016 / Revised: 27 April 2016 / Accepted: 9 May 2016 / Published: 13 May 2016
(This article belongs to the Collection Health Care and Diabetes)
View Full-Text   |   Download PDF [271 KB, uploaded 13 May 2016]

Abstract

Propolis contains a variety of bioactive components and possesses many biological properties. This study was designed to evaluate potential effects of Brazilian green propolis on glucose metabolism and antioxidant function in patients with type 2 diabetes mellitus (T2DM). In the 18-week randomized controlled study, enrolled patients with T2DM were randomly assigned to Brazilian green propolis group (900 mg/day) (n = 32) and control group (n = 33). At the end of the study, no significant difference was found in serum glucose, glycosylated hemoglobin, insulin, aldose reductase or adiponectin between the two groups. However, serum GSH and total polyphenols were significantly increased, and serum carbonyls and lactate dehydrogenase activity were significantly reduced in the Brazilian green propolis group. Serum TNF-α was significantly decreased, whereas serum IL-1β and IL-6 were significantly increased in the Brazilian green propolis group. It is concluded that Brazilian green propolis is effective in improving antioxidant function in T2DM patients. View Full-Text
Keywords: Brazilian green propolis; type 2 diabetes mellitus; antioxidant function Brazilian green propolis; type 2 diabetes mellitus; antioxidant function
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Zhao, L.; Pu, L.; Wei, J.; Li, J.; Wu, J.; Xin, Z.; Gao, W.; Guo, C. Brazilian Green Propolis Improves Antioxidant Function in Patients with Type 2 Diabetes Mellitus. Int. J. Environ. Res. Public Health 2016, 13, 498.

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