Next Article in Journal
Mitigating Physiological Responses to Layoff Threat: An Experimental Test of the Efficacy of Two Coping Interventions
Next Article in Special Issue
Salivary Alpha-Amylase Reactivity in Breast Cancer Survivors
Previous Article in Journal
Assessment of the Spatial and Temporal Variations of Water Quality for Agricultural Lands with Crop Rotation in China by Using a HYPE Model
Previous Article in Special Issue
Depressive Mood and Testosterone Related to Declarative Verbal Memory Decline in Middle-Aged Caregivers of Children with Eating Disorders
Article Menu

Export Article

Open AccessReview
Int. J. Environ. Res. Public Health 2016, 13(3), 337; doi:10.3390/ijerph13030337

Salivary Cortisol Reactivity in Preterm Infants in Neonatal Intensive Care: An Integrative Review

1
Department of Social and Welfare Studies, Division of Nursing Science, Linköping University, Norrköping 60174, Sweden
2
Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore 119077, Singapore
*
Author to whom correspondence should be addressed.
Academic Editors: Catherine Bielajew and Guergana Mileva
Received: 12 January 2016 / Revised: 5 March 2016 / Accepted: 14 March 2016 / Published: 18 March 2016
(This article belongs to the Special Issue Stress Biomarkers)
View Full-Text   |   Download PDF [440 KB, uploaded 18 March 2016]   |  

Abstract

Recently, more and more researchers have been using salivary cortisol reactivity to evaluate stress in preterm infants in the neonatal intensive care unit (NICU). The aim of this integrative literature review was to summarize the evidence of interventions leading to a change in salivary cortisol from the baseline in preterm infants in the NICU. The electronic databases of PubMed, CINAHL, Web of Science, and Scopus were searched for relevant studies. The inclusion criteria were studies with preterm infants exposed to an intervention evaluated by salivary cortisol reactivity before discharge from the NICU, which were published in English. In total, 16 studies were included. Eye-screening examination and heel lance provoked an increase in the salivary cortisol level. Music, prone position, and co-bedding among twins decreased the salivary cortisol level. Several studies reported a low rate of successful saliva sampling or did not use control groups. Future studies need to focus on non-painful interventions in order to learn more about salivary cortisol regulation in preterm infants. Moreover, these studies should use study designs comprising homogenous gestational and postnatal age groups, control groups, and reliable analysis methods that are able to detect cortisol in small amounts of saliva. View Full-Text
Keywords: cortisol; infants; neonatal care; nursing; pain; preterm; saliva; stress cortisol; infants; neonatal care; nursing; pain; preterm; saliva; stress
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Mörelius, E.; He, H.-G.; Shorey, S. Salivary Cortisol Reactivity in Preterm Infants in Neonatal Intensive Care: An Integrative Review. Int. J. Environ. Res. Public Health 2016, 13, 337.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top