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Int. J. Environ. Res. Public Health 2016, 13(10), 1028; doi:10.3390/ijerph13101028

Beneficial Effects of UV-Radiation: Vitamin D and beyond

1
Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria
2
Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria
3
Department of Cardiology, Swiss Cardiovascular Center Bern, Bern University Hospital, Freiburgstrasse 8, Bern 3010, Switzerland
4
Bad Gleichenberg Clinic, Schweizereiweg 4, Bad Gleichenberg 8344, Austria
*
Author to whom correspondence should be addressed.
Academic Editors: Daniela Haluza, Stana Simic and Hanns Moshammer
Received: 1 September 2016 / Revised: 12 October 2016 / Accepted: 13 October 2016 / Published: 19 October 2016
(This article belongs to the Special Issue UV-Radiation: From Physics to Impacts)
View Full-Text   |   Download PDF [327 KB, uploaded 19 October 2016]

Abstract

Aside from its well-known effects on bone and mineral metabolism, vitamin D may also play an important role in extra-skeletal processes like immunologic diseases, cancer, or cardiovascular diseases. Even though meta-analyses showed that vitamin D supplementation reduces fractures, falls, and overall mortality, its potential benefits did not find universal acclaim. Several health care authorities published Recommended Dietary Allowances (RDAs) for vitamin D, most of them ranging from 600 to 800 international units (IU) per day, corresponding to a serum level of 25-hydroxyvitamin D of at least 20 ng/mL (50 nmol/L). However, studies conducted in the general population revealed a much lower overall intake of vitamin D than the proposed RDAs. Thus, strategies to increase the vitamin D intake in the general population, e.g., food fortification or vitamin D supplementation, are needed to match the existing evidence and recommendations. Therefore, several currently ongoing projects aim to investigate the effect of vitamin D supplementation in the general population and try to establish food-based solutions to improve vitamin D status. View Full-Text
Keywords: vitamin D; 25(OH)D; UV-radiation; review vitamin D; 25(OH)D; UV-radiation; review
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Trummer, C.; Pandis, M.; Verheyen, N.; Grübler, M.R.; Gaksch, M.; Obermayer-Pietsch, B.; Tomaschitz, A.; Pieber, T.R.; Pilz, S.; Schwetz, V. Beneficial Effects of UV-Radiation: Vitamin D and beyond. Int. J. Environ. Res. Public Health 2016, 13, 1028.

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