An Evaluation on the Effect of Health Education and of Low-Dose Statin in Dyslipidemia among Low-Income Rural Uyghur Adults in Far Western China: A Comprehensive Intervention Study
Abstract
:1. Introduction
2. Methods
2.1. Ethics Statement
2.2. Study Design and Patients
2.3. Interventions
2.4. Data Collection
2.4.1. Questionnaire Survey
2.4.2. Physical Examination and Blood Lipid Examination
2.4.3. Definitions
2.4.4. Statistical Analysis
3. Result
3.1. Basic Characteristics of the Study Population
Variables | Intervention Group (n = 347) | Control Group (n = 308) | t/χ2 | p |
---|---|---|---|---|
Sex (n,%) | 2.118 | 0.146 | ||
male | 182(52.4%) | 144(46.8%) | ||
female | 165(47.6%) | 164(53.2%) | ||
Age (years) | 45.86 ± 15.32 | 45.37 ± 17.55 | 0.346 | 0.729 |
Height (cm) | 163.44 ± 6.99 | 162.80 ± 10.34 | 0.187 | 0.853 |
Weight (kg) | 65.46 ± 10.78 | 66.28 ± 11.91 | 1.803 | 0.093 |
WHR | 0.85 ± 0.06 | 0.86 ± 0.07 | 1.841 | 0.066 |
BMI (kg/m2) | 21.51 ± 2.61 | 21.54 ± 2.83 | 0.132 | 0.895 |
TG (mmol/L) | 1.43 ± 0.78 | 1.29 ± 0.73 | 1.933 | 0.054 |
TC ( mmol/L) | 4.39 ± 1.05 | 4.15 ± 1.20 | 2.891 | 0.089 |
HDL-C ( mmol/L) | 0.96 ± 0.23 | 1.02 ± 0.22 | 1.796 | 0.073 |
LDL-C (mmol/L) | 2.44 ± 0.69 | 2.39 ± 0.86 | 0.634 | 0.526 |
SBP (mmHg) | 129.28 ± 22.73 | 130.76 ± 21.16 | 0.752 | 0.457 |
DBP (mmHg) | 80.94 ± 13.79 | 81.00 ± 14.19 | 0.043 | 0.966 |
FBG (mmol/L) | 4.23 ± 0.73 | 4.09 ± 0.78 | 1.695 | 0.091 |
Current smoking state (%) | 1.345 | 0.510 | ||
no | 323(93.1%) | 295(95.8%) | ||
yes | 24(6.9%) | 13(4.2%) | ||
Current drinking state (%) | 1.052 | 0.591 | ||
no | 342(98.6%) | 304(98.7%) | ||
yes | 5(1.4%) | 4(1.3%) |
3.2. Comparison of Lipid Levels
Variable | Baseline | Post-1 Year | Post-2 Year | Outcome | F | p | |
---|---|---|---|---|---|---|---|
Intervention group | TG | 1.43 ± 0.78 | 1.42 ± 1.03 | 1.40 ± 1.11 * | 1.39 ± 0.81 *,## | 25.611 | 0.000 |
TC | 4.39 ± 1.05 | 4.22 ± 0.94 ## | 4.10 ± 0.83 ## | 4.15 ± 0.92 ## | 0.603 | 0.547 | |
HDL-C | 0.96 ± 0.23 | 1.01 ± 0.37 ** | 1.09 ± 0.25 * | 1.22 ± 0.41 *,## | 76.877 | 0.000 | |
LDL-C | 2.44 ± 0.69 | 2.37 ± 0.59 **,## | 2.10 ± 0.50 *,# | 2.12 ± 0.62 *,# | 98.453 | 0.000 | |
Control group | TG | 1.29 ± 0.73 | 1.37 ± 0.85 ** | 1.41 ± 0.72 ** | 1.50 ± 0.91 * | 22.493 | 0.000 |
TC | 4.15 ± 0.72 | 4.01 ± 0.92 | 3.80 ± 0.86 | 3.95 ± 0.84 | 0.412 | 0.703 | |
HDL-C | 1.02 ± 0.22 | 0.93 ± 0.32 ** | 1.06 ± 0.29 ** | 1.10 ± 0.36 ** | 2.385 | 0.032 | |
LDL-C | 2.39 ± 0.86 | 2.43 ± 0.81 ** | 2.32 ± 0.70 ** | 2.24 ± 0.77 ** | 1.754 | 0.041 |
3.3. Comparison of the Control Rate of Dyslipidemia
Groups | n | Control | % | χ2 | p |
---|---|---|---|---|---|
Intervention Group | 347 | 134 | 38.61 | 116.263 | 0.000 |
Control Group | 308 | 11 | 3.57 |
3.4. Lipid Changes in the Amplitude of the Survey Population
Variable | Intervention Group (n = 347) | Mean Percent Change, % ± SE (Median) | Control Group (n = 308) | Mean Percent Change, % ± SE (Median) | |
---|---|---|---|---|---|
TG, mmol/L | Baseline | 1.43 ± 0.78 | −2.80 ± 0.08 (0.55) | 1.29 ± 0.73 | 16.28 ± 0.52 (10.99) |
Outcome | 1.39 ± 0.81 | 1.50 ± 0.91 ** | |||
TC, mmol/L | Baseline | 4.39 ± 1.05 | −5.47 ± 0.09 (−3.81) | 4.40 ± 0.12 | −4.55 ± 0.19 (−2.16) |
Outcome | 4.15 ± 0.92 | 4.20 ± 0.84 ** | |||
HDL-C, mmol/L | Baseline | 0.96 ± 0.23 | 27.08 ± 0.07 (17.40) | 1.02 ± 0.22 | 7.84 ± 0.02 (6.32) |
Outcome | 1.22 ± 0.41 | 1.10 ± 0.36 ** | |||
LDL-C, mmol/L | Baseline | 2.44 ± 0.69 | −13.11 ± 0.20 (−9.26) | 2.43 ± 0.86 | −6.17 ± 0.06 (−6.57) |
Outcome | 2.12 ± 0.62 | 2.28 ± 0.77 * |
3.5. Comparison of Body Mass Index
3.6. Comparison of Knowledge, Attitude, Behavior Score
Scores | Intervention Group | Control Group | ||
---|---|---|---|---|
Baseline | Outcome | Baseline | Outcome | |
Knowledge scores | 1.00 ± 1.19 * | 3.32 ± 1.29 # | 1.05 ± 1.15 | 1.39 ± 1.18 |
Attitude scores | 0.60 ± 0.73 * | 2.07 ± 0.87 # | 0.66 ± 0.80 | 0.82 ± 0.92 |
Behavior scores | 0.45 ± 0.71 * | 1.11 ± 0.83 # | 0.50 ± 0.81 | 0.70 ± 0.96 |
Total average scores | 2.05 ± 1.82 * | 6.50 ± 3.30 # | 2.20 ± 1.92 | 2.91 ± 2.31 * |
4. Discussion
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Ma, J.; Guo, S.; Ma, R.; Zhang, J.; Liu, J.; Ding, Y.; Zhang, M.; Guo, H.; He, J.; Yan, Y.; et al. An Evaluation on the Effect of Health Education and of Low-Dose Statin in Dyslipidemia among Low-Income Rural Uyghur Adults in Far Western China: A Comprehensive Intervention Study. Int. J. Environ. Res. Public Health 2015, 12, 11410-11421. https://doi.org/10.3390/ijerph120911410
Ma J, Guo S, Ma R, Zhang J, Liu J, Ding Y, Zhang M, Guo H, He J, Yan Y, et al. An Evaluation on the Effect of Health Education and of Low-Dose Statin in Dyslipidemia among Low-Income Rural Uyghur Adults in Far Western China: A Comprehensive Intervention Study. International Journal of Environmental Research and Public Health. 2015; 12(9):11410-11421. https://doi.org/10.3390/ijerph120911410
Chicago/Turabian StyleMa, Jiaolong, Shuxia Guo, Rulin Ma, Jingyu Zhang, Jiaming Liu, Yusong Ding, Mei Zhang, Heng Guo, Jia He, Yizhong Yan, and et al. 2015. "An Evaluation on the Effect of Health Education and of Low-Dose Statin in Dyslipidemia among Low-Income Rural Uyghur Adults in Far Western China: A Comprehensive Intervention Study" International Journal of Environmental Research and Public Health 12, no. 9: 11410-11421. https://doi.org/10.3390/ijerph120911410