Short-Term Effect of Ambient Temperature and the Risk of Stroke: A Systematic Review and Meta-Analysis
AbstractBackground and Purpose: The relationship between stroke and short-term temperature changes remains controversial. Therefore, we conducted a systematic review and meta-analysis to investigate the association between stroke and both high and low temperatures, and health assessment. Methods: We searched PubMed, Embase, Cochrane, China National Knowledge Infrastructure (CNKI) and Wanfang Data up to 14 September 2014. Study selection, quality assessment, and author-contractions were steps before data extraction. We converted all estimates effects into relative risk (RR) per 1 °C increase/decrease in temperature from 75th to 99th or 25th to 1st percentiles, then conducted meta-analyses to combine the ultimate RRs, and assessed health impact among the population. Results: 20 articles were included in the final analysis. The overall analysis showed a positive relationship between 1 °C change and the occurrence of major adverse cerebrovascular events (MACBE), 1.1% (95% confidence intervals (CI), 0.6 to 1.7) and 1.2% (95% CI, 0.8 to 1.6) increase for hot and cold effects separately. The same trends can be found in both effects of mortality and the cold effect for morbidity. Hot temperature acted as a protective factor of hemorrhage stroke (HS), −1.9% (95% CI, −2.8 to −0.9), however, it acted as a risk factor for ischemic stroke (IS), 1.2% (95% CI, 0.7 to 1.8). Conclusion: Short-term changes of both low and high temperature had statistically significant impacts on MACBE. View Full-Text
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Lian, H.; Ruan, Y.; Liang, R.; Liu, X.; Fan, Z. Short-Term Effect of Ambient Temperature and the Risk of Stroke: A Systematic Review and Meta-Analysis. Int. J. Environ. Res. Public Health 2015, 12, 9068-9088.
Lian H, Ruan Y, Liang R, Liu X, Fan Z. Short-Term Effect of Ambient Temperature and the Risk of Stroke: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health. 2015; 12(8):9068-9088.Chicago/Turabian Style
Lian, Hui; Ruan, Yanping; Liang, Ruijuan; Liu, Xiaole; Fan, Zhongjie. 2015. "Short-Term Effect of Ambient Temperature and the Risk of Stroke: A Systematic Review and Meta-Analysis." Int. J. Environ. Res. Public Health 12, no. 8: 9068-9088.