Next Article in Journal
Prevalence and Determinants of Anemia and Iron Deficiency in Kuwait
Previous Article in Journal
Urbanization and Mental Health in China: Linking the 2010 Population Census with a Cross-Sectional Survey
Article Menu

Export Article

Open AccessArticle
Int. J. Environ. Res. Public Health 2015, 12(8), 9025-9035;

Residence in Proximity of an Iron Foundry and Risk of Lung Cancer in the Municipality of Trieste, Italy, 1995–2009

SOC Epidemiologia e Biostatistica, IRCCS Centro di Riferimento Oncologico di Aviano, 33081 Aviano (PN), Italy
Istituto di Igiene ed Epidemiologia clinica, DSMB Università degli Studi di Udine, 33100 Udine, Italy
DSM Università degli Studi di Trieste, 34100 Trieste, Italy
SOC Igiene ed Epidemiologia Clinica, Azienda Ospedaliero Universitaria di Udine, 33100 Udine, Italy
Agenzia Regionale Protezione Ambientale, Friuli Venezia Giulia, 33057 Palmanova (UD), Italy
Direzione Centrale Salute, Friuli Venezia Giulia, Servizio Regionale di Epidemiologia, 33100 Udine, Italy
Registro Tumori del Friuli Venezia Giulia, 33081 Aviano (PN), Italy
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Received: 1 June 2015 / Revised: 24 July 2015 / Accepted: 27 July 2015 / Published: 31 July 2015
View Full-Text   |   Download PDF [212 KB, uploaded 31 July 2015]


We assessed the risk of lung cancer in people living near the iron foundry located within the city of Trieste, Northeastern Italy. Between 1995 and 2009, all incident cases of lung cancer and corresponding population were considered. A deposition model of the foundry-specific emissions of SO2 defined: “nearby”, “urban”, and “outlying” areas. Rate ratios (RRs) and annual percent changes (APCs) were computed. Among nearby residents, significantly increased risks of lung cancer were noted in men below age 75 years (RR = 1.35 vs. urban area; 95% CI: 1.03–1.77). In women, and in men aged 75 years or older, no significant RRs were observed. Conversely, people living in the outlying area appeared to be at lower risk than residents in the urban area- in all age groups, in men (RR = 0.87; 95% CI: 0.78–0.98) and in women (RR = 0.74; 95% CI: 0.62–0.88). Negative statistically significant APC was recorded in men living in urban areas (–2.6%), whereas in women APC significantly increased among those living in the urban area (+2.3%). Multiple interpretations for this observation are plausible, since several factors might have modified and/or confounded the risk of lung cancer, including air pollution from other sources and road traffic, occupational and smoking patterns. View Full-Text
Keywords: air pollution; iron foundry; geocoded; lung cancer; northeastern Italy air pollution; iron foundry; geocoded; lung cancer; northeastern Italy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Bidoli, E.; Barbone, F.; Collarile, P.; Valent, F.; Zanier, L.; Daris, F.; Gini, A.; Birri, S.; Serraino, D. Residence in Proximity of an Iron Foundry and Risk of Lung Cancer in the Municipality of Trieste, Italy, 1995–2009. Int. J. Environ. Res. Public Health 2015, 12, 9025-9035.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top