Next Article in Journal
The Expansion of the Economic Frontier and the Diffusion of Violence in the Amazon
Previous Article in Journal
Building-Related Symptoms among Office Employees Associated with Indoor Carbon Dioxide and Total Volatile Organic Compounds
Article Menu

Export Article

Open AccessArticle
Int. J. Environ. Res. Public Health 2015, 12(6), 5846-5861; doi:10.3390/ijerph120605846

Effect of Pesticide Exposure on Immunological, Hematological and Biochemical Parameters in Thai Orchid Farmers— A Cross-Sectional Study

1
Center of Excellence on Environmental Health and Toxicology (EHT), and Laboratory of Immunology, Kampangpetch 6 Road, Lak-si, Bangkok 10210, Thailand
2
Department of Mathematics, Faculty of Science, Mahidol University, Rama VI Road, Ratchathewi, Bangkok 10400, Thailand
3
Chulabhorn Graduate Institute, Kampangpetch 6 Road, Lak-si, Bangkok 10210, Thailand
*
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Received: 1 April 2015 / Accepted: 19 May 2015 / Published: 27 May 2015
View Full-Text   |   Download PDF [722 KB, uploaded 29 May 2015]   |  

Abstract

Various studies have found that many Thai orchid farmers used excessive amounts of pesticides without proper protective gear, but no toxicological study has been made. This cross-sectional study aimed to evaluate the immunological, hematological and biochemical statuses of these farmers. Sixty four orchid farmers and 60 controls were studied. Plasma cholinesterase activity, the percentage and absolute number of B lymphocytes (CD19+) were significantly lower in the farmers group (3966.32 ± 1165.48 U/L, 11.61 ± 4.09% and 312.26 ± 164.83 cells/mm3, respectively) as compared to those of controls (5048.85 ± 1139.40 U/L, 14.32 ± 4.23%, 420.34 ± 195.18 cells/mm3, respectively). There was a statistically significant higher level of serum IgE among the orchid farmers (0.031 ± 0.011 mg/dL vs. 0.018 ± 0.007 mg/dL) but not IgG, IgA and IgM, levels. Serum lysozyme level, lymphocyte proliferative responses to mitogens, hematological parameters and kidney function test, were not significantly different between the two groups. The liver function profiles showed significantly lower levels of albumin and serum protein in the farmer group. Thus frequent pesticide exposure resulted in subtle changes of some biological parameters. These changes, though may not be clinically significant, strongly indicated that caution in handing pesticides by these farmers is warranted. View Full-Text
Keywords: pesticide exposure; immunological and biochemical alterations; orchid farmers; cross-sectional study pesticide exposure; immunological and biochemical alterations; orchid farmers; cross-sectional study
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Aroonvilairat, S.; Kespichayawattana, W.; Sornprachum, T.; Chaisuriya, P.; Siwadune, T.; Ratanabanangkoon, K. Effect of Pesticide Exposure on Immunological, Hematological and Biochemical Parameters in Thai Orchid Farmers— A Cross-Sectional Study. Int. J. Environ. Res. Public Health 2015, 12, 5846-5861.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top