Next Article in Journal
Can Metabolic Disorders in Aging Men Contribute to Prostatic Hyperplasia Eligible for Transurethral Resection of the Prostate (TURP)?
Previous Article in Journal
Decreasing Health Disparities for People with Disabilities through Improved Communication Strategies and Awareness
Article Menu

Export Article

Correction published on 16 June 2015, see Int. J. Environ. Res. Public Health 2015, 12(6), 6892-6893.

Open AccessArticle
Int. J. Environ. Res. Public Health 2015, 12(3), 3317-3326; doi:10.3390/ijerph120303317

Monoamine Oxidase A Promoter Variable Number of Tandem Repeats (MAOA-uVNTR) in Alcoholics According to Lesch Typology

1
Institute of Psychology, Department of Clinical Psychology, University of Szczecin, Krakowska 69, 71-017 Szczecin, Poland
2
University Center for Education, University of Szczecin, Szwoleżerów 18a, 71-062 Szczecin, Poland
3
Department of Psychiatry, Pomeranian Medical University, Broniewskiego 26, 71-460 Szczecin, Poland
4
Department of Psychiatry, Vienna University, Waehringer Guertel 18–20, A-1090 Vienna, Austria
5
Department of Nursing, Pomeranian Medical University, Żołnierska 48, 71-210 Szczecin, Poland
6
Institute of Psychiatry and Neurology, Department of Pharmacology, Sobieskiego 9, 02-957 Warszawa, Poland
7
Department of Orthopedics, Pomeranian Medical University, Unii Lubelskiej 1, 71-460 Szczecin, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Received: 8 January 2015 / Revised: 9 March 2015 / Accepted: 9 March 2015 / Published: 19 March 2015
View Full-Text   |   Download PDF [691 KB, uploaded 19 March 2015]

Abstract

Background: The aim of this study was to examine the association between the MAOA-uVNTR gene polymorphism in a homogeneous subgroups of patients with alcohol dependence categorized according to Lesch’s typology. Methods: DNA was provided from alcohol dependent (AD) patients (n = 370) and healthy control subjects (n = 168) all of Polish descent. The history of alcoholism was obtained using the Polish version of the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA). Samples were genotyped using PCR methods. Results: We found no association between alcohol dependence and MAOA gene polymorphism. Conclusions: Lesch typology is a clinical consequence of the disease and its phenotypic description is too complex for a simple genetic analysis. View Full-Text
Keywords: alcohol dependence; MAOA; Lesch’s typology alcohol dependence; MAOA; Lesch’s typology
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Samochowiec, A.; Chęć, M.; Kopaczewska, E.; Samochowiec, J.; Lesch, O.; Grochans, E.; Jasiewicz, A.; Bienkowski, P.; Kołodziej, Ł.; Grzywacz, A. Monoamine Oxidase A Promoter Variable Number of Tandem Repeats (MAOA-uVNTR) in Alcoholics According to Lesch Typology. Int. J. Environ. Res. Public Health 2015, 12, 3317-3326.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top