Next Article in Journal
Effects of Air Pollution on the Risk of Congenital Anomalies: A Systematic Review and Meta-Analysis
Previous Article in Journal
Serum Lipid Profiles, Lipid Ratios and Chronic Kidney Disease in a Chinese Population
Previous Article in Special Issue
Interaction of Intercellular Adhesion Molecule 1 (ICAM1) Polymorphisms and Environmental Tobacco Smoke on Childhood Asthma
Int. J. Environ. Res. Public Health 2014, 11(8), 7636-7641; doi:10.3390/ijerph110807636

Associations Between Subjective Symptoms and Serum Immunoglobulin E Levels During Asian Dust Events

1,2,* , 3
Received: 8 April 2014 / Revised: 15 July 2014 / Accepted: 16 July 2014 / Published: 29 July 2014
(This article belongs to the Special Issue Genetic Impact on the Development of Allergic Disease)
View Full-Text   |   Download PDF [448 KB, 30 July 2014; original version 29 July 2014]   |   Browse Figure


Asian dust is a seasonal meteorological phenomenon caused by the displacement of atmospheric pollutants from the Mongolian and Chinese deserts. Although the frequency of Asian dust events and atmospheric dust levels have steadily increased in the eastern Asia region, the effects on human health remain poorly understood. In the present study, the impact of Asian dust on human health was determined in terms of allergic reactions. A total of 25 healthy volunteers were tested for a relationship between serum immunoglobulin E (IgE) levels and subjective symptoms during a 3-day Asian dust event recorded in April 2012. They filled daily questionnaires on the severity of nasal, pharyngeal, ocular, respiratory, and skin symptoms by a self-administered visual analog scale. Serum levels of non-specific IgE and 33 allergen-specific IgE molecules were analyzed. Spearman rank-correlation analysis revealed significant positive associations between nasal symptom scores and 2 microbial-specific IgE levels (Penicillium and Cladosporium). Microbes migrate vast distances during Asian dust events by attaching themselves to dust particles. Therefore, some of these symptoms may be associated with type 1 allergic reactions to certain type of microbes.
Keywords: Asian dust; type 1 allergic reaction; immunoglobulin E Asian dust; type 1 allergic reaction; immunoglobulin E
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
MDPI and ACS Style

Otani, S.; Onishi, K.; Mu, H.; Hosoda, T.; Kurozawa, Y.; Ikeguchi, M. Associations Between Subjective Symptoms and Serum Immunoglobulin E Levels During Asian Dust Events. Int. J. Environ. Res. Public Health 2014, 11, 7636-7641.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


Cited By

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert