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Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.
Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan
Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan
Natural Medicinal Products Research Center and Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan
Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan
* Authors to whom correspondence should be addressed.
Received: 20 July 2011; in revised form: 22 August 2011 / Accepted: 5 September 2011 / Published: 14 September 2011
Abstract: Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a weak inhibitory effect on the release of elastase by human neutrophils.
Keywords: menelloide; lindenane; germacrane; sesquiterpenoid; Menella; elastase
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Kao, S.-Y.; Su, J.-H.; Hwang, T.-L.; Sheu, J.-H.; Wen, Z.-H.; Wu, Y.-C.; Sung, P.-J. Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.. Mar. Drugs 2011, 9, 1534-1542.
Kao S-Y, Su J-H, Hwang T-L, Sheu J-H, Wen Z-H, Wu Y-C, Sung P-J. Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.. Marine Drugs. 2011; 9(9):1534-1542.
Kao, Shih-Yao; Su, Jui-Hsin; Hwang, Tsong-Long; Sheu, Jyh-Horng; Wen, Zhi-Hong; Wu, Yang-Chang; Sung, Ping-Jyun. 2011. "Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.." Mar. Drugs 9, no. 9: 1534-1542.