Mar. Drugs 2011, 9(9), 1534-1542; doi:10.3390/md9091534
Short Note

Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.

Shih-Yao Kao 1,2 email, Jui-Hsin Su 1,2,3 email, Tsong-Long Hwang 4 email, Jyh-Horng Sheu 3,5 email, Zhi-Hong Wen 3,5 email, Yang-Chang Wu 6,7,* email and Ping-Jyun Sung 1,2,3,5,8,* email
1 Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan 2 National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan 3 Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan 4 Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan 5 Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan 6 Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan 7 Natural Medicinal Products Research Center and Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan 8 Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan
* Authors to whom correspondence should be addressed.
Received: 20 July 2011; in revised form: 22 August 2011 / Accepted: 5 September 2011 / Published: 14 September 2011
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Abstract: Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a weak inhibitory effect on the release of elastase by human neutrophils.
Keywords: menelloide; lindenane; germacrane; sesquiterpenoid; Menella; elastase

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Cite This Article

MDPI and ACS Style

Kao, S.-Y.; Su, J.-H.; Hwang, T.-L.; Sheu, J.-H.; Wen, Z.-H.; Wu, Y.-C.; Sung, P.-J. Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.. Mar. Drugs 2011, 9, 1534-1542.

AMA Style

Kao S-Y, Su J-H, Hwang T-L, Sheu J-H, Wen Z-H, Wu Y-C, Sung P-J. Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.. Marine Drugs. 2011; 9(9):1534-1542.

Chicago/Turabian Style

Kao, Shih-Yao; Su, Jui-Hsin; Hwang, Tsong-Long; Sheu, Jyh-Horng; Wen, Zhi-Hong; Wu, Yang-Chang; Sung, Ping-Jyun. 2011. "Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.." Mar. Drugs 9, no. 9: 1534-1542.

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