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Mar. Drugs 2011, 9(9), 1534-1542; doi:10.3390/md9091534

Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.

1
Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan
2
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan
3
Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
4
Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan
5
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
6
Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan
7
Natural Medicinal Products Research Center and Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan
8
Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan
*
Authors to whom correspondence should be addressed.
Received: 20 July 2011 / Revised: 22 August 2011 / Accepted: 5 September 2011 / Published: 14 September 2011
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Abstract

Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a weak inhibitory effect on the release of elastase by human neutrophils.
Keywords: menelloide; lindenane; germacrane; sesquiterpenoid; Menella; elastase menelloide; lindenane; germacrane; sesquiterpenoid; Menella; elastase
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Kao, S.-Y.; Su, J.-H.; Hwang, T.-L.; Sheu, J.-H.; Wen, Z.-H.; Wu, Y.-C.; Sung, P.-J. Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.. Mar. Drugs 2011, 9, 1534-1542.

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