Mar. Drugs 2011, 9(9), 1543-1553; doi:10.3390/md9091543
Article

Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides

1email, 1,2,3email, 1email, 1email, 1email, 4email, 1,5,* email and 2,3,* email
Received: 11 August 2011; in revised form: 6 September 2011 / Accepted: 6 September 2011 / Published: 16 September 2011
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Five new nardosinane-type sesquiterpenoids, paralemnolins Q–U (15), along with three known compounds (68), were isolated from the Formosan soft coral Paralemnalia thyrsoides. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods, and the absolute configuration of 1 was determined by the application of Mosher’s method on 1. Among these metabolites, 1 and 3 are rarely found nardosinane-type sesquiterpenoids, possessing novel polycyclic structures. Compounds 1, 3, 6 and 7 were found to possess neuroprotective activity.
Keywords: soft coral; Paralemnalia thyrsoides; nardosinane; neuroprotective activity
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MDPI and ACS Style

Huang, C.-Y.; Su, J.-H.; Chen, B.-W.; Wen, Z.-H.; Hsu, C.-H.; Dai, C.-F.; Sheu, J.-H.; Sung, P.-J. Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides. Mar. Drugs 2011, 9, 1543-1553.

AMA Style

Huang C-Y, Su J-H, Chen B-W, Wen Z-H, Hsu C-H, Dai C-F, Sheu J-H, Sung P-J. Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides. Marine Drugs. 2011; 9(9):1543-1553.

Chicago/Turabian Style

Huang, Chiung-Yao; Su, Jui-Hsin; Chen, Bo-Wei; Wen, Zhi-Hong; Hsu, Chi-Hsin; Dai, Chang-Feng; Sheu, Jyh-Horng; Sung, Ping-Jyun. 2011. "Nardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides." Mar. Drugs 9, no. 9: 1543-1553.


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