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Mar. Drugs 2011, 9(5), 690-695; doi:10.3390/md9050690
Article

Deoxyuridines from the Marine Sponge Associated Actinomycete Streptomyces microflavus

1,* , 2
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3
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4
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 and
1,*
Received: 9 March 2011 / Revised: 3 April 2011 / Accepted: 13 April 2011 / Published: 26 April 2011
(This article belongs to the Special Issue Biomedicines from Marine Symbioses)
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Abstract

One new nucleoside derivative, named 3-acetyl-5-methyl-2′-deoxyuridine (1), along with two known compounds 3,5-dimethyl-2′-deoxyuridine (2) and 3-methyl-2′-deoxyuridine (3), were isolated from the cultures of Streptomyces microflavus. This strain was an associated actinomycete isolated from the marine sponge Hymeniacidon perlevis collected from the coast of Dalian (China). Their structures were elucidated by detailed NMR and MS spectroscopic analysis as well as comparison with literature data.
Keywords: actinomycete; Streptomyces microflavus; Hymeniacidon perlevis; deoxyuridine actinomycete; Streptomyces microflavus; Hymeniacidon perlevis; deoxyuridine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Li, K.; Li, Q.-L.; Ji, N.-Y.; Liu, B.; Zhang, W.; Cao, X.-P. Deoxyuridines from the Marine Sponge Associated Actinomycete Streptomyces microflavus. Mar. Drugs 2011, 9, 690-695.

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