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Statistical Research on Marine Natural Products Based on Data Obtained between 1985 and 2008
School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Xingang Xilu, Guangzhou 510275, China
Zhongshan School of Medicine, Sun Yat-Sen University, Zhongshan Erlu, Guangzhou 510080, China
Key Laboratory of Functional Molecules from Oceanic Microorganisms (Sun Yat-sen University), Department of Education of Guangdong Province, Guangzhou 510080, China
* Authors to whom correspondence should be addressed.
Received: 10 February 2011; in revised form: 4 March 2011 / Accepted: 24 March 2011 / Published: 29 March 2011
Abstract: Since the 1960s, more than 20,000 compounds were discovered from marine organisms. In this paper we performed a quantitative analysis for the novel marine natural products reported between 1985 and 2008. The data was extracted mainly from the reviews of Faulkner and Blunt [1–26]. The organisms producing these marine natural products are divided into three major biological classes: marine microorganisms (including phytoplankton), marine algae and marine invertebrate. The marine natural products are divided into seven classes based on their chemical structure: terpenoids, steroids (including steroidal saponins), alkaloids, ethers (including ketals), phenols (including quinones), strigolactones, and peptides. The distribution and the temporal trend of these classes (biological classes and chemical structure classes) were investigated. We hope this article provides a comprehensive perspective on the research of marine natural products.
Keywords: marine natural products; quantitative analysis; novel compounds
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Hu, G.-P.; Yuan, J.; Sun, L.; She, Z.-G.; Wu, J.-H.; Lan, X.-J.; Zhu, X.; Lin, Y.-C.; Chen, S.-P. Statistical Research on Marine Natural Products Based on Data Obtained between 1985 and 2008. Mar. Drugs 2011, 9, 514-525.
Hu G-P, Yuan J, Sun L, She Z-G, Wu J-H, Lan X-J, Zhu X, Lin Y-C, Chen S-P. Statistical Research on Marine Natural Products Based on Data Obtained between 1985 and 2008. Marine Drugs. 2011; 9(4):514-525.
Hu, Gu-Ping; Yuan, Jie; Sun, Li; She, Zhi-Gang; Wu, Jue-Heng; Lan, Xiu-Jian; Zhu, Xun; Lin, Yong-Cheng; Chen, Sheng-Ping. 2011. "Statistical Research on Marine Natural Products Based on Data Obtained between 1985 and 2008." Mar. Drugs 9, no. 4: 514-525.