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Mar. Drugs 2011, 9(2), 196-223; doi:10.3390/md9020196
Review

Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae

1,2
, 2,* , 3
 and 1,*
Received: 22 December 2010; in revised form: 15 January 2011 / Accepted: 26 January 2011 / Published: 8 February 2011
(This article belongs to the Special Issue Marine Biomaterials)
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Abstract: Sulfated polysaccharides and their lower molecular weight oligosaccharide derivatives from marine macroalgae have been shown to possess a variety of biological activities. The present paper will review the recent progress in research on the structural chemistry and the bioactivities of these marine algal biomaterials. In particular, it will provide an update on the structural chemistry of the major sulfated polysaccharides synthesized by seaweeds including the galactans (e.g., agarans and carrageenans), ulvans, and fucans. It will then review the recent findings on the anticoagulant/antithrombotic, antiviral, immuno-inflammatory, antilipidemic and antioxidant activities of sulfated polysaccharides and their potential for therapeutic application.
Keywords: sulfated polysaccharide; marine macroalgae; carbohydrate structure; bioactivity; oligosaccharides sulfated polysaccharide; marine macroalgae; carbohydrate structure; bioactivity; oligosaccharides
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Jiao, G.; Yu, G.; Zhang, J.; Ewart, H.S. Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae. Mar. Drugs 2011, 9, 196-223.

AMA Style

Jiao G, Yu G, Zhang J, Ewart HS. Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae. Marine Drugs. 2011; 9(2):196-223.

Chicago/Turabian Style

Jiao, Guangling; Yu, Guangli; Zhang, Junzeng; Ewart, H. S. 2011. "Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae." Mar. Drugs 9, no. 2: 196-223.



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