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Halogenated Compounds from Marine Algae
IPIMAR, Av. de Brasília, 1449-006 Lisboa, Portugal
Centro de Química e Bioquímica/Departamento de Química e Bioquímica da Faculdade de Ciências da Universidade de Lisboa, Ed C8, Piso 5, Campo Grande, 1749-016 Lisboa, Portugal
* Author to whom correspondence should be addressed.
Received: 30 June 2010; in revised form: 23 July 2010 / Accepted: 2 August 2010 / Published: 9 August 2010
Abstract: Marine algae produce a cocktail of halogenated metabolites with potential commercial value. Structures exhibited by these compounds go from acyclic entities with a linear chain to complex polycyclic molecules. Their medical and pharmaceutical application has been investigated for a few decades, however other properties, such as antifouling, are not to be discarded. Many compounds were discovered in the last years, although the need for new drugs keeps this field open as many algal species are poorly screened. The ecological role of marine algal halogenated metabolites has somehow been overlooked. This new research field will provide valuable and novel insight into the marine ecosystem dynamics as well as a new approach to comprehending biodiversity. Furthermore, understanding interactions between halogenated compound production by algae and the environment, including anthropogenic or global climate changes, is a challenging target for the coming years. Research of halogenated metabolites has been more focused on macroalgae than on phytoplankton. However, phytoplankton could be a very promising material since it is the base of the marine food chain with quick adaptation to environmental changes, which undoubtedly has consequences on secondary metabolism. This paper reviews recent progress on this field and presents trends on the role of marine algae as producers of halogenated compounds.
Keywords: marine algae; halogenated compounds; biotechnological applications; ecological role
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MDPI and ACS Style
Cabrita, M.T.; Vale, C.; Rauter, A.P. Halogenated Compounds from Marine Algae. Mar. Drugs 2010, 8, 2301-2317.
Cabrita MT, Vale C, Rauter AP. Halogenated Compounds from Marine Algae. Marine Drugs. 2010; 8(8):2301-2317.
Cabrita, Maria Teresa; Vale, Carlos; Rauter, Amélia Pilar. 2010. "Halogenated Compounds from Marine Algae." Mar. Drugs 8, no. 8: 2301-2317.