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Potential Anti-HIV Agents from Marine Resources: An Overview
Marine Biochemistry Laboratory, Department of Chemistry, Pukyong National University, Busan 608-737, Korea
Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Korea
* Author to whom correspondence should be addressed.
Received: 8 October 2010; in revised form: 25 November 2010 / Accepted: 26 November 2010 / Published: 29 November 2010
Abstract: Human immunodeficiency virus (HIV) infection causes acquired immune deficiency syndrome (AIDS) and is a global public health issue. Anti-HIV therapy involving chemical drugs has improved the life quality of HIV/AIDS patients. However, emergence of HIV drug resistance, side effects and the necessity for long-term anti-HIV treatment are the main reasons for failure of anti-HIV therapy. Therefore, it is essential to isolate novel anti-HIV therapeutics from natural resources. Recently, a great deal of interest has been expressed regarding marine-derived anti-HIV agents such as phlorotannins, sulfated chitooligosaccharides, sulfated polysaccharides, lectins and bioactive peptides. This contribution presents an overview of anti-HIV therapeutics derived from marine resources and their potential application in HIV therapy.
Keywords: anti-HIV agents; AIDS; phlorotannins; marine resources
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MDPI and ACS Style
Vo, T.-S.; Kim, S.-K. Potential Anti-HIV Agents from Marine Resources: An Overview. Mar. Drugs 2010, 8, 2871-2892.
Vo T-S, Kim S-K. Potential Anti-HIV Agents from Marine Resources: An Overview. Marine Drugs. 2010; 8(12):2871-2892.
Vo, Thanh-Sang; Kim, Se-Kwon. 2010. "Potential Anti-HIV Agents from Marine Resources: An Overview." Mar. Drugs 8, no. 12: 2871-2892.