Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
AbstractTwo new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with those of 3 and other related compounds [1-5]. Compounds 1 and 2 are closely related to cylindricines A and B, lacking C-4 oxygenation found in cylindricines and having a butyl instead of a hexyl appendage. NOE experiments on compounds 1 and 2 suggested the A/B ring fusion to be cis.
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Issa, H.H.; Tanaka, J.; Rachmat, R.; Setiawan, A.; Trianto, A.; Higa, T. Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian. Mar. Drugs 2005, 3, 78-83.
Issa HH, Tanaka J, Rachmat R, Setiawan A, Trianto A, Higa T. Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian. Marine Drugs. 2005; 3(3):78-83.Chicago/Turabian Style
Issa, Hamad H.; Tanaka, Junichi; Rachmat, Rachmaniar; Setiawan, Andi; Trianto, Agus; Higa, Tatsuo. 2005. "Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian." Mar. Drugs 3, no. 3: 78-83.