Identification of Renieramycin A as an Antileishmanial Substance in a Marine Sponge Neopetrosia sp.
Abstract
:Introduction
Results and Discussion
Conclusions
Experimental
General
Animal material
Antileishmanial assay
Isolation
#C | δCa | δHa | HMBC | δHb | δHb,c |
---|---|---|---|---|---|
1 | 60.0 | 3.60 | C-8 | 3.62 | 3.60 |
3 | d | 2.65 | 2.64 | 2.64 | |
4 | d | 2.63 | 2.75 | 2.75 | |
1.2 | 1.26 | 1.26 | |||
5 | 187.1 | ||||
6 | 128.8 | ||||
7 | 157.7 | ||||
8 | 190.5 | ||||
9 | 144.0 | ||||
10 | d | ||||
11 | 56.9 | 4.04 | C-13 | 4.04 | 4.04 |
13 | 62.6 | 3.14 | 3.18 | 3.18 | |
14 | 71.5 | 3.62 | 4.43 | 4.44 | |
15 | 188.0 | ||||
16 | 130.2 | ||||
17 | 156.9 | ||||
18 | d | ||||
19 | d | ||||
20 | d | ||||
21 | 43.0 | 3.2 | 3.18 | 3.18 | |
2.7 | 2.71 | 2.71 | |||
22 | 64.0 | 4.45 | C-9 | 4.48 | 4.47 |
4.27 | C-24 | 4.19 | 4.19 | ||
24 | 168.9 | ||||
25 | 128.3 | ||||
26 | 140.2 | 5.94 | 5.92 | 5.92 | |
6-Me | 8.6 | 1.85 s | C-5, 6, 7 | 1.93 | 1.91 |
7-OMe | 61.2 | 3.95 s | C-7 | 4.00 | 4.00 |
12-NMe | 42.5 | 2.46 s | C-11, 13 | 2.43 | 2.43 |
16-Me | 8.3 | 1.91 s | C-15, 16, 17 | 1.93 | 1.92 |
17-OMe | 61.2 | 3.92 s | C-17 | 4.01 | 4.01 |
25-Me | 20.8 | 1.53 s | C-25, 26 | 1.57 | 1.55 |
26-Me | 15.8 | 1.72 d | C-25, 26 | 1.80 | 1.78 |
Acknowledgments
- Samples Availability: Not available.
References and Notes
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Nakao, Y.; Shiroiwa, T.; Murayama, S.; Matsunaga, S.; Goto, Y.; Matsumoto, Y.; Fusetani, N. Identification of Renieramycin A as an Antileishmanial Substance in a Marine Sponge Neopetrosia sp. Mar. Drugs 2004, 2, 55-62. https://doi.org/10.3390/md202055
Nakao Y, Shiroiwa T, Murayama S, Matsunaga S, Goto Y, Matsumoto Y, Fusetani N. Identification of Renieramycin A as an Antileishmanial Substance in a Marine Sponge Neopetrosia sp. Marine Drugs. 2004; 2(2):55-62. https://doi.org/10.3390/md202055
Chicago/Turabian StyleNakao, Yoichi, Takeru Shiroiwa, Shuhei Murayama, Shigeki Matsunaga, Yasuyuki Goto, Yoshitsugu Matsumoto, and Nobuhiro Fusetani. 2004. "Identification of Renieramycin A as an Antileishmanial Substance in a Marine Sponge Neopetrosia sp." Marine Drugs 2, no. 2: 55-62. https://doi.org/10.3390/md202055