Next Article in Journal
Bis-Indolyl Benzenoids, Hydroxypyrrolidine Derivatives and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Aspergillus candidus KUFA0062
Previous Article in Journal
Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs
Previous Article in Special Issue
Dual Roles of Ascidian Chondromodulin-1: Promoting Cell Proliferation Whilst Suppressing the Growth of Tumor Cells
Article Menu
Issue 4 (April) cover image

Export Article

Open AccessReview
Mar. Drugs 2018, 16(4), 118; https://doi.org/10.3390/md16040118

Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods

Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Qld, Australia
*
Authors to whom correspondence should be addressed.
Received: 7 February 2018 / Revised: 21 March 2018 / Accepted: 29 March 2018 / Published: 5 April 2018
(This article belongs to the Collection Bioactive Compounds from Marine Invertebrates)
View Full-Text   |   Download PDF [24757 KB, uploaded 3 May 2018]   |  

Abstract

A diverse range of predatory marine gastropods produce toxins, yet most of these molecules remain uncharacterized. Conus species have received the most attention from researchers, leading to several conopeptides reaching clinical trials. This review aims to summarize what is known about bioactive compounds isolated from species of neglected marine gastropods, especially in the Turridae, Terebridae, Babyloniidae, Muricidae, Buccinidae, Colubrariidae, Nassariidae, Cassidae, and Ranellidae families. Multiple species have been reported to contain bioactive compounds with potential toxic activity, but most of these compounds have not been characterized or even clearly identified. The bioactive properties and potential applications of echotoxins and related porins from the Ranellidae family are discussed in more detail. Finally, the review concludes with a call for research on understudied species. View Full-Text
Keywords: toxins; marine gastropods; salivary glands; peptides; Ranellidae; echotoxins toxins; marine gastropods; salivary glands; peptides; Ranellidae; echotoxins
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Turner, A.H.; Craik, D.J.; Kaas, Q.; Schroeder, C.I. Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods. Mar. Drugs 2018, 16, 118.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top