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Mar. Drugs 2015, 13(7), 4296-4309; doi:10.3390/md13074296

New Scalarane Sesterterpenoids from the Formosan Sponge Ircinia felix

1
Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan
2
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan
3
Department of Pharmacy & Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 907, Taiwan
4
Department of Sport, Health and Leisure, Cheng Shiu University, Kaohsiung 833, Taiwan
5
School of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, Taiwan
6
Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan
7
Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan
8
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan
9
Department of Marine Biotechnology and Resources, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
*
Authors to whom correspondence should be addressed.
Academic Editor: Anake Kijjoa
Received: 4 June 2015 / Revised: 7 July 2015 / Accepted: 8 July 2015 / Published: 14 July 2015
View Full-Text   |   Download PDF [823 KB, uploaded 14 July 2015]   |  

Abstract

Five new scalarane sesterterpenoids, felixins A–E (15), were isolated from the Formosan sponge Ircinia felix. The structures of scalaranes 15 were elucidated on the basis of spectroscopic analysis. Cytotoxicity of scalaranes 15 against the proliferation of a limited panel of tumor cell lines was evaluated. View Full-Text
Keywords: Ircinia felix; sponge; scalarane; sesterterpenoid; cytotoxicity Ircinia felix; sponge; scalarane; sesterterpenoid; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Lai, Y.-Y.; Lu, M.-C.; Wang, L.-H.; Chen, J.-J.; Fang, L.-S.; Wu, Y.-C.; Sung, P.-J. New Scalarane Sesterterpenoids from the Formosan Sponge Ircinia felix. Mar. Drugs 2015, 13, 4296-4309.

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